DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3117 and PLG

DIOPT Version :9

Sequence 1:NP_608722.2 Gene:CG3117 / 33484 FlyBaseID:FBgn0031471 Length:347 Species:Drosophila melanogaster
Sequence 2:NP_000292.1 Gene:PLG / 5340 HGNCID:9071 Length:810 Species:Homo sapiens


Alignment Length:322 Identity:84/322 - (26%)
Similarity:126/322 - (39%) Gaps:78/322 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 CLSSNLCVPRENCREEMPFFDFSSTIECSDEEVCCEKSNVIGMSKSPPQHSVDTLLRTSYPNALD 88
            |.::|   ||:       .:|:....:|:.....|.|..|                   .|....
Human   543 CYTTN---PRK-------LYDYCDVPQCAAPSFDCGKPQV-------------------EPKKCP 578

  Fly    89 GSPQVFGDQTKPNQFPWVTALFAK-GSYLGGGSLITPGLVLTAAHILAGLSPNDIMVRAGEWDLS 152
            |. .|.|....|:.:||..:|..: |.:..||:||:|..||||||.|                  
Human   579 GR-VVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCL------------------ 624

  Fly   153 SSEKLNPPMDRQVIKIMEHEAFNYSSGA--------------NDLALLFLDSPFELRANIQTIRL 203
              ||...|...:|| :..|:..|.....              .|:|||.|.||..:...:....|
Human   625 --EKSPRPSSYKVI-LGAHQEVNLEPHVQEIEVSRLFLEPTRKDIALLKLSSPAVITDKVIPACL 686

  Fly   204 PIPDKTF-DRRICTVAGWGMRSSTDVDIQTIQQKVDLPVVESSKCQRQLRLTKMGSNYQLPASLM 267
            |.|:... ||..|.:.|||....|..  ..:.::..|||:|:..|.|...|     |.::.::.:
Human   687 PSPNYVVADRTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFL-----NGRVQSTEL 744

  Fly   268 CAGG-EEGRDVCSLFGGFALFCSLDDDPNRYEQAGIVSFGVGCGQANVPTTFTHVSKFMEWI 328
            |||. ..|.|.|....|..|.|.   :.::|...|:.|:|:||.:.|.|..:..||:|:.||
Human   745 CAGHLAGGTDSCQGDSGGPLVCF---EKDKYILQGVTSWGLGCARPNKPGVYVRVSRFVTWI 803

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3117NP_608722.2 Tryp_SPc 95..329 CDD:238113 72/251 (29%)
Tryp_SPc 95..328 CDD:214473 70/249 (28%)
PLGNP_000292.1 PAN_AP_HGF <38..97 CDD:238532
KR 101..183 CDD:214527
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 126..145
KR 183..263 CDD:214527
KR 273..354 CDD:214527
KR 375..456 CDD:214527
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 396..416
KR 479..560 CDD:214527 5/26 (19%)
Tryp_SPc 580..803 CDD:214473 71/254 (28%)
Tryp_SPc 581..804 CDD:238113 73/254 (29%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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