Protein Alignment CG3117 and PRSS50

DIOPT Version :10

• Sequence 1: NP_608722.2
• Gene: CG3117 / 33484
• FlyBaseID: FBgn0031471
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_037402.1
• Gene: PRSS50 / 29122
• HGNCID: 17910
• Length: 385
• Species: Homo sapiens
• Alignment Length: 386
• Identity: 92/386 - (23%)
• Similarity: 157/386 - (40%)
• Gaps: 68/386 - (17%)

  Fly     1 MSRLCTSL----------------VIILGLILSSGGTHIC---------LS-------SNLCVPR 33
            |.|.|.::                :::|.|:|.|.|   |         ||       |..|||:
Human     1 MGRWCQTVARGQRPRTSAPSRAGALLLLLLLLRSAG---CWGAGEAPGALSTADPADQSVQCVPK 62

  Fly    34 ENCREEMPFFDFSSTIECSDEEVCCEKSNVIGMSKSPPQHSVDTLLRTSYPNALDGSPQVFGDQT 98
            ..|....|...:.:....:......|....:...|..|..|..    .||    :..|.:...:.
Human    63 ATCPSSRPRLLWQTPTTQTLPSTTMETQFPVSEGKVDPYRSCG----FSY----EQDPTLRDPEA 119

  Fly    99 KPNQFPWVTALFAKGSYLGGGSLITPGLVLTAAHILAGLSPNDIM--VRAGE-WDLSSSEKLNPP 160
            ...::||:.::.|.|:::..|::|....|||.||.|..   .|::  ||.|. |   ..:.....
Human   120 VARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIW---RDVIYSVRVGSPW---IDQMTQTA 178

  Fly   161 MDRQVIKIMEHEAF------NYSSGANDLALLFLDSPFELRANIQTIRLPIPDKTF-DRRICTVA 218
            .|..|::::.|..:      ::...|||:.||.|....:....::.|.||..|... |...|||.
Human   179 SDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVT 243

  Fly   219 GWGMRSSTDV--DIQTIQQKVDLPVVESSKCQR-QLRLTKMGSNYQ-LPASLMCAGGEEGRDVCS 279
            |||:..:..:  ..:|||:| ::.::.:.:|.. ....||:.:..| :.:.:|||........|.
Human   244 GWGLSKADGMWPQFRTIQEK-EVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCY 307

  Fly   280 LFGGFALFCSLDDDPNRYEQAGIVSFGVGCGQANVPTTFTHVSKFMEWINPHLE-QVLSVP 339
            ...|..|.||::   ..:...|:||:|.||.::..|..:..||.:..||...|. |.|::|
Human   308 ELTGEPLVCSME---GTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQALALP 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3117	NP_608722.2	Tryp_SPc	95..329	CDD:238113	63/247 (26%)
PRSS50	NP_037402.1	Tryp_SPc	118..353	CDD:238113	62/244 (25%)