DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18557 and prss60.3

DIOPT Version :9

Sequence 1:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	XP_002662541.2	Gene:	prss60.3 / 335152	ZFINID:	ZDB-GENE-030131-7092	Length:	330	Species:	Danio rerio

Alignment Length:	358	Identity:	84/358 - (23%)
Similarity:	136/358 - (37%)	Gaps:	112/358 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MWRRVIFIRCCFWTLTETGAPCGLQMECVPQGLCKTSAWNQNAISWPSPCQRSESCCHSSQKLVI 65
            |||    :.|...||          :.||...|.:.:...|
Zfish     3 MWR----LTCATLTL----------LICVKGSLSQLNVCGQ------------------------ 29

  Fly    66 GAPLNCGKSNPNGLGGTVEEVVDQAKPNEFPWTVAL-MQNLINFFGAGTLVTENIVITAAHLMLD 129
             |||     |...:||.      .|.|..:||.|:| .......|..|:|::...|:||||.:
Zfish    30 -APL-----NTRIVGGV------NASPGSWPWQVSLHSPKYGGHFCGGSLISSEWVLTAAHCL-- 80

  Fly   130 KTINDFGIIGGAWDLKQLAGKTIQ----WRTATRIVS---HPDFNKMTGANNIALIVLETSFVMK 187
            ..:::..::      ..|..:|.|    :.|:..:..   |..:|..|..|:|||:.|.::....
Zfish    81 SGVSETTLV------VYLGRRTQQGINIYETSRNVAKSFVHSSYNSNTNDNDIALLRLSSAVTFT 139

  Fly   188 PPIGPICWP------TSGVSFDRERCLVAGWG---------RPDFLAKNYSYKQKKIDLPIVSRS 237
            ..|.|:|..      ::|.|     ..:.|||         .|..|.:..        :|:|:..
Zfish   140 NYIRPVCLAAQNSVYSAGTS-----SWITGWGDIQAGVNLPAPGILQETM--------IPVVAND 191

  Fly   238 DCESLLRRTAFVQSFQLDPTILCAG-GERGRDACIGDGGSPL---MCPIPGHPAIYELVGIVNSG 298
            .|.:||      .|..:...::||| .:.|:|.|.||.|.|:   :|      .::...||.:.|
Zfish   192 RCNALL------GSGTVTNNMICAGLTQGGKDTCQGDSGGPMVTRLC------TVWVQAGITSWG 244

  Fly   299 FSCGLENVPALYTNISHMRPWIEKQLNDELNKP 331
            :.|...|.|.:||.:|..:.||..:::  ||||
Zfish   245 YGCADPNSPGVYTRVSQYQSWISSKIS--LNKP 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	64/261 (25%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	62/256 (24%)
prss60.3	XP_002662541.2	Tryp_SPc	36..269	CDD:238113	66/271 (24%)
prss60.3	XP_002662541.2	Somatomedin_B	294..328	CDD:321959
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587637
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930