DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18557 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_001121000.1	Gene:	Tmprss13 / 300682	RGDID:	1310872	Length:	539	Species:	Rattus norvegicus

Alignment Length:	289	Identity:	76/289 - (26%)
Similarity:	128/289 - (44%)	Gaps:	38/289 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 PSPCQRSESCCHSSQKLVIGAPLNCGKSNPNG--LGGTVEEVVDQAKPNEFPWTVALMQNLINFF 109
            ||....|..|.|            ||.....|  :||.:      ...:::||.|:|.....:..
  Rat   277 PSRRYVSLQCAH------------CGLRAMTGRIVGGAL------TSESKWPWQVSLHFGTTHIC 323

  Fly   110 GAGTLVTENIVITAAHLML---DKTINDFGIIGGAWDLKQLAGKTIQWRTATRIVSHPDFNKMTG 171
            | |||:....|:||||...   :|.:..:.:..|..:|.||.    :..:.::|:.:.::.....
  Rat   324 G-GTLIDAQWVLTAAHCFFVTREKILEGWKVYAGTSNLHQLP----EAASISQIIINGNYTDEQD 383

  Fly   172 ANNIALIVLETSFVMKPPIGPICWPTSGVSFD-RERCLVAGWGRPDFLAKNYSYKQKKIDLPIVS 235
            ..:|||:.|.....:...|.|.|.|..|.:|. .|.|.:.|:|:.....:..|...:::.:.::.
  Rat   384 DYDIALVRLSKPLTLSAHIHPACLPLHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLID 448

  Fly   236 RSDCESLLRRTAFVQSFQLDPTILCAGGER-GRDACIGDGGSPLMCPIPGHPAIYELVGIVNSGF 299
            ...|...|     |....|.|.::|||..| |||:|.||.|.||:|.....   :.|.|:.:.|.
  Rat   449 FKKCNDYL-----VYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNR---WYLAGVTSWGT 505

  Fly   300 SCGLENVPALYTNISHMRPWIEKQLNDEL 328
            .||.:|.|.:||.::.:.|||.:::..|:
  Rat   506 GCGQKNKPGVYTKVTEVLPWIYRKMESEV 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	65/239 (27%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	63/234 (27%)
Tmprss13	NP_001121000.1	WWbp	<1..69	CDD:304964
		SRCR_2	203..292	CDD:292133	7/26 (27%)
		SRCR	216..288	CDD:278931	4/10 (40%)
		Tryp_SPc	297..526	CDD:214473	65/247 (26%)
		Tryp_SPc	298..526	CDD:238113	65/246 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910