DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18557 and Plau

DIOPT Version :9

Sequence 1:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_037217.3	Gene:	Plau / 25619	RGDID:	3343	Length:	432	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	90/373 - (24%)
Similarity:	150/373 - (40%)	Gaps:	100/373 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 QGLCKTSAWNQNAISWPSPCQRSESC-CHSSQKLVIGAPLNCGKSNPN-----------GLGGTV 83
            :|...|....:..::|.||....::. .|.|..|.:|...:....||:           ||...|
  Rat    79 RGKANTDTKGRPCLAWNSPAVLQQTYNAHRSDALSLGLGKHNYCRNPDNQRRPWCYVQIGLKQFV 143

  Fly    84 EEVVDQ-----AKPN------------------------EF------PWTVAL-MQNL----INF 108
            :|.:.|     .||:                        ||      ||..|: ::|.    .:|
  Rat   144 QECMVQDCSLSKKPSSTVDQQGFQCGQKALRPRFKIVGGEFTVVENQPWFAAIYLKNKGGSPPSF 208

  Fly   109 FGAGTLVTENIVITAAHLMLDKTINDFGII--GGA-----------WDLKQLAGKTIQWRTATRI 160
            ...|:|::...|.:|.|..:::...:..::  |.:           ::::||
  Rat   209 KCGGSLISPCWVASATHCFVNQPKKEEYVVYLGQSKRNSYNPGEMKFEVEQL------------- 260

  Fly   161 VSHPDFNKMTGA--NNIALIVLETSF--VMKP--PIGPICWPT--SGVSFDRERCLVAGWGRPDF 217
            :.|.||:..|.|  |:|||:.:.||.  ..:|  .|..||.|.  ....|..: |.:.|:|:..
  Rat   261 ILHEDFSDETLAFHNDIALLKIRTSTGQCAQPSRTIQTICLPPRFGDAPFGSD-CEITGFGQES- 323

  Fly   218 LAKNYSY-KQKKID-LPIVSRSDCESLLRRTAFVQSFQLDPTILCAGG-ERGRDACIGDGGSPLM 279
             |.:|.| |..|:. :.|:|...|     :.......:::..:|||.. |...|:|.||.|.||:
  Rat   324 -ATDYFYPKDLKMSVVKIISHEQC-----KQPHYYGSEINYKMLCAADPEWKTDSCSGDSGGPLI 382

  Fly   280 CPIPGHPAIYELVGIVNSGFSCGLENVPALYTNISHMRPWIEKQLNDE 327
            |.|.|.|.   |.|||:.|..|..:|.|.:||.:|:...||:..:.:|
  Rat   383 CNIDGRPT---LSGIVSWGSGCAEKNKPGVYTRVSYFLNWIQSHIGEE 427

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	74/298 (25%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	71/288 (25%)
Plau	NP_037217.3	Binds urokinase plasminogen activator surface receptor	34..57
		KR	67..152	CDD:238056	16/72 (22%)
		Connecting peptide	152..178		2/25 (8%)
		Tryp_SPc	178..420	CDD:214473	69/265 (26%)
		Tryp_SPc	179..423	CDD:238113	71/267 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910