DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18557 and F9

DIOPT Version :9

Sequence 1:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_113728.1	Gene:	F9 / 24946	RGDID:	2589	Length:	462	Species:	Rattus norvegicus

Alignment Length:	369	Identity:	89/369 - (24%)
Similarity:	146/369 - (39%)	Gaps:	92/369 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 GAPCGLQMEC-VPQGLCKTSAWN--QNAI-------------------SWPSPCQRSESCCHSSQ 61
            |..|.|...| :..|.||....|  .|.|                   :.|.||.| .|..::|:
  Rat   118 GRNCELDATCSIKNGRCKQFCKNSPDNKIICSCTEGYQLAEDQKSCEPAVPFPCGR-VSVAYNSK 181

  Fly    62 KLVIGAPLNCGKSNPNGLGGTVEEVVD----------------------------QAKPNEFPWT 98
            |:.....:   .||.: .|.:.|.::|                            .|||.:.||.
  Rat   182 KITRAETV---FSNTD-YGNSTELILDDITNSTILDNLTENSEPINDFTRVVGGENAKPGQIPWQ 242

  Fly    99 VALMQNLINFFGAGTLVTENIVITAAHLMLDKTINDFGIIGGAWDLKQLAGKTIQWRTATRIVSH 163
            | ::...|..|..|.::.|..::||||.:  |..:...::.|..::.: ...|.|.|...|.:.|
  Rat   243 V-ILNGEIEAFCGGAIINEKWIVTAAHCL--KPGDKIEVVAGEHNIDE-KEDTEQRRNVIRTIPH 303

  Fly   164 PDFNKMTG--ANNIALIVLETSFVMKPPIGPICWPT-----------SGVSFDRERCLVAGWGRP 215
            ..:|....  :::|||:.|:...::...:.|||...           ||        .|:|||:.
  Rat   304 HQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFLKFGSG--------YVSGWGKV 360

  Fly   216 DFLAKNYSYKQKKIDLPIVSRSDCESLLRRTAFVQSFQLDPTILCAG-GERGRDACIGDGGSPLM 279
            ....:..|..| .:.:|:|.|:.|   ||.|    .|.:...:.||| .|.|:|:|.||.|.|.:
  Rat   361 FNKGRQASILQ-YLRVPLVDRATC---LRST----KFSIYNNMFCAGYREGGKDSCEGDSGGPHV 417

  Fly   280 CPIPGHPAIYELVGIVNSGFSCGLENVPALYTNISHMRPWIEKQ 323
            ..:.|...   |.||::.|..|.::....:||.:|....||:::
  Rat   418 TEVEGTSF---LTGIISWGEECAMKGKYGIYTKVSRYVNWIKEK 458

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	68/276 (25%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	65/243 (27%)
F9	NP_113728.1	GLA	21..85	CDD:214503
		EGF_CA	86..122	CDD:238011	1/3 (33%)
		FXa_inhibition	127..163	CDD:291342	7/35 (20%)
		Tryp_SPc	227..455	CDD:214473	65/250 (26%)
		Tryp_SPc	228..458	CDD:238113	67/252 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000