DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18557 and F11

DIOPT Version :9

Sequence 1:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_082342.1	Gene:	F11 / 109821	MGIID:	99481	Length:	624	Species:	Mus musculus

Alignment Length:	327	Identity:	84/327 - (25%)
Similarity:	130/327 - (39%)	Gaps:	74/327 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 CFWTLTETGAP----------CGLQME-CVPQGLCKTSAWNQNAISWPSPCQRSESCCHSSQKLV 64
            |:..|:..|:|          .|..:. |....:|.|
Mouse   348 CYLKLSSNGSPTRILHGRGGISGYSLRLCKMDNVCTT---------------------------- 384

  Fly    65 IGAPLNCGKSNPNGLGGTVEEVVDQAKPNEFPWTVALMQNLINFFGAGTLVTENIVITAAHLMLD 129
                    |.||..:||..      :...|:||.|.|..:..:..| |:::....::||||....
Mouse   385 --------KINPRVVGGAA------SVHGEWPWQVTLHISQGHLCG-GSIIGNQWILTAAHCFSG 434

  Fly   130 -KTINDFGIIGGAWDLKQLAGKTIQWRTATRIVSHPDFNKMTGANNIALIVLETSFVMKPPIGPI 193
             :|.....:.||..:..::...|..:|....|: |..:.......:|||:.||::........||
Mouse   435 IETPKKLRVYGGIVNQSEINEGTAFFRVQEMII-HDQYTTAESGYDIALLKLESAMNYTDFQRPI 498

  Fly   194 CWPTSGVSFDRE----RCLVAGWGRPDFLAKNYSYKQKKIDLPIVSRSDCESLLRRTAFVQSFQL 254
            |.|:.|   ||.    .|.|.|||......:..|..| |..:|:||..:|::..||      .::
Mouse   499 CLPSKG---DRNAVHTECWVTGWGYTALRGEVQSTLQ-KAKVPLVSNEECQTRYRR------HKI 553

  Fly   255 DPTILCAG-GERGRDACIGDGGSPLMCPIPGHPAIYELVGIVNSGFSCGLENVPALYTNISHMRP 318
            ...::||| .|.|:|.|.||.|.||.|...|   ::.||||.:.|..||.:..|.:|||::....
Mouse   554 TNKMICAGYKEGGKDTCKGDSGGPLSCKYNG---VWHLVGITSWGEGCGQKERPGVYTNVAKYVD 615

  Fly   319 WI 320
            ||
Mouse   616 WI 617

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	71/239 (30%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	69/235 (29%)
F11	NP_082342.1	APPLE	20..103	CDD:128519
		APPLE	110..193	CDD:128519
		APPLE	200..283	CDD:128519
		APPLE	291..376	CDD:128519	5/27 (19%)
		Tryp_SPc	389..617	CDD:214473	71/248 (29%)
		Tryp_SPc	390..617	CDD:238113	71/247 (29%)
		Heparin-binding. /evidence=ECO:0000250	547..550		0/2 (0%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910