DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18557 and MASP2

DIOPT Version :9

Sequence 1:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_006601.2	Gene:	MASP2 / 10747	HGNCID:	6902	Length:	686	Species:	Homo sapiens

Alignment Length:	247	Identity:	78/247 - (31%)
Similarity:	120/247 - (48%)	Gaps:	20/247 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 QAKPNEFPWTVALMQNLINFFGAGTLVTENIVITAAHLMLDKTINDFGIIGGAWDLKQLAGKTIQ 153
            :|||.:|||.|.::....   .||.|:.:|.|:||||.:.::..:...:......||:|:....|
Human   450 KAKPGDFPWQVLILGGTT---AAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTLKRLSPHYTQ 511

  Fly   154 -WRTATRIVSHPDFNKMTG-ANNIALIVLETSFVMKPPIGPICWP-TSGVSFDRERCL--VAGWG 213
             |..|..|  |..:....| .|:||||.|....|:...|.|||.| ....||.|...:  .:|||
Human   512 AWSEAVFI--HEGYTHDAGFDNDIALIKLNNKVVINSNITPICLPRKEAESFMRTDDIGTASGWG 574

  Fly   214 --RPDFLAKNYSYKQKKIDLPIVSRSDCESLLRRTAFVQSFQLDPTILCAGGER-GRDACIGDGG 275
              :..|||:|..|    :|:|||....|.:...:..:.:. .:...:||||.|. |:|:|.||.|
Human   575 LTQRGFLARNLMY----VDIPIVDHQKCTAAYEKPPYPRG-SVTANMLCAGLESGGKDSCRGDSG 634

  Fly   276 SPLMCPIPGHPAIYELVGIVNSG-FSCGLENVPALYTNISHMRPWIEKQLND 326
            ..|:. :......:.:.|||:.| .:||......:||.:.:..||||..::|
Human   635 GALVF-LDSETERWFVGGIVSWGSMNCGEAGQYGVYTKVINYIPWIENIISD 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	77/242 (32%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	74/238 (31%)
MASP2	NP_006601.2	CUB	28..134	CDD:214483
		EGF_CA	138..176	CDD:214542
		CUB	184..293	CDD:278839
		CCP	300..361	CDD:214478
		Sushi	366..430	CDD:278512
		Tryp_SPc	444..679	CDD:214473	74/239 (31%)
		Tryp_SPc	445..682	CDD:238113	77/242 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910