DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18557 and akt1

DIOPT Version :9

Sequence 1:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	XP_004917247.1	Gene:	akt1 / 100490038	XenbaseID:	XB-GENE-484953	Length:	493	Species:	Xenopus tropicalis

Alignment Length:	314	Identity:	66/314 - (21%)
Similarity:	99/314 - (31%)	Gaps:	115/314 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    75 NPNGLGGTVEEVVDQAKP------NEFPWTVALMQNLINFFGAGTLVTENIVITAAHLMLDKTIN 133
            :|:...|..|..|..:||      |||.:...|.:..   ||...||.|...
Frog   125 SPSDNSGAEEMEVSHSKPKHKVTMNEFEYLKLLGKGT---FGKVILVKEKAT------------- 173

  Fly   134 DFGIIGGAWDLKQLAGKTIQWR-------TATRIVS---HPDFNKMTGANNIALIVLETS----- 183
                 |..:.:|.|..:.|..:       |..|::.   ||           .|..|:.|
Frog   174 -----GRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHP-----------FLTALKYSFQTHD 222

  Fly   184 ---FVMKPPIGPICWPTSGVSF---DRERCLVAGWGR---------PDFL--AKNYSYKQKKIDL 231
               |||:       :...|..|   .|||.......|         .|:|  .||..|:..|::.
Frog   223 RLCFVME-------YANGGELFFHLSRERIFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLEN 280

  Fly   232 PIVSRSDCESLLRRTAFVQSFQLDPTILCAGGERGRDACIGDGGS-PLMCPIPGH--PAIYE--- 290
            .::   |.:..::.|.|.         ||..|       |.||.: ...|..|.:  |.:.|
Frog   281 LML---DKDGHIKITDFG---------LCKEG-------IKDGATMKTFCGTPEYLAPEVLEDND 326

  Fly   291 --------LVGIVNSGFSCGLENVPALYTNISHMRPWIEKQLNDELNKPYKTFP 336
                    .:|:|.....||  .:|  :.|..|.: ..|..|.:|:..|....|
Frog   327 YGRAVDWWGLGVVMYEMMCG--RLP--FYNQDHEK-LFELILMEEIRFPRTLLP 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	58/286 (20%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	57/281 (20%)
akt1	XP_004917247.1	PH_PKB	4..111	CDD:269947
akt1	XP_004917247.1	PKc_like	125..491	CDD:419665	66/314 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910