DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18557 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_608721.1	Gene:	CG18557 / 33483	FlyBaseID:	FBgn0031470	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	302	Identity:	79/302 - (26%)
Similarity:	129/302 - (42%)	Gaps:	40/302 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 NAISWPSPCQRSESCCHSSQKLVIGAP-----LNCG---KSNPNGLGGTVEEVVDQAKPNEFPWT 98
            |..|:..|.:.......|..|..:|..     :.||   |.:...:||.:      :...:|||.
Zfish   254 NQTSFQQPVKIHNITNSSKTKCSLGMVTALKCIACGSRPKFSARIVGGNL------SAEGQFPWQ 312

  Fly    99 VAL-MQNLINFFGAGTLVTENIVITAAHLMLDKTINDFGIIGGAW-----DLKQLAGKTIQWRTA 157
            |:| .||  .....|:::|...::||||.:       :||....:     .|.:|....::....
Zfish   313 VSLHFQN--EHLCGGSIITSRWILTAAHCV-------YGIAYPMYWMVYAGLTELPLNAVKAFAV 368

  Fly   158 TRIVSHPDFNKMTGANNIALIVLETSFVMKPPIGPICWPTSGVSF-DRERCLVAGWGRPDFLAKN 221
            .:|:.|..:......::|||:.|.........:.|||.|..|..| |.:.|.::|||..:. ..:
Zfish   369 EKIIYHSRYRPKGLDHDIALMKLAQPLTFNGMVEPICLPNFGEQFEDGKMCWISGWGATED-GGD 432

  Fly   222 YSYKQKKIDLPIVSRSDCESLLRRTAFVQSFQLDPTILCAGG-ERGRDACIGDGGSPLMCPIPGH 285
            .|..|....:|::|...|.    :....|.: |...::|||. :.|.|:|.||.|.||.|.   .
Zfish   433 ASVSQHCASVPLISNKACS----QPEVYQGY-LTAGMICAGYLDGGTDSCQGDSGGPLACE---D 489

  Fly   286 PAIYELVGIVNSGFSCGLENVPALYTNISHMRPWIEKQLNDE 327
            .:|::|||..:.|..|..:|.|.:||.|:....||..|:..|
Zfish   490 SSIWKLVGATSWGQGCAEKNKPGVYTRITQSLTWIHLQMERE 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18557	NP_608721.1	Tryp_SPc	88..323	CDD:238113	66/242 (27%)
CG18557	NP_608721.1	Tryp_SPc	90..320	CDD:214473	64/237 (27%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	8/37 (22%)
		Tryp_SPc	298..525	CDD:238113	67/250 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910