DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2975 and C1GALT1

DIOPT Version :9

Sequence 1:	NP_608719.1	Gene:	CG2975 / 33481	FlyBaseID:	FBgn0031468	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_064541.1	Gene:	C1GALT1 / 56913	HGNCID:	24337	Length:	363	Species:	Homo sapiens

Alignment Length:	293	Identity:	125/293 - (42%)
Similarity:	174/293 - (59%)	Gaps:	18/293 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 LAARLFNETRVLCMVLTSPKTHHTRAIHIKRTWGRRCNKLIFMSTKADKELGSVALNVREGYSNL 140
            :|..|:.:.|:||.|:|.|:....:|.|:|.||.:||||::|||::.:|:..:|.|..:||...|
Human    79 IAENLYQKVRILCWVMTGPQNLEKKAKHVKATWAQRCNKVLFMSSEENKDFPAVGLKTKEGRDQL 143

  Fly   141 WPKTRAALQYVYKHHFQKYDWFLKADDDTYFIMENLRAFLHAHNFREPVYFGNKFRQHVKEGYMS 205
            :.||..|.|||::|:.:..|||||||||||.|::|||..|..::..||:|||.:|:.:||:||||
Human   144 YWKTIKAFQYVHEHYLEDADWFLKADDDTYVILDNLRWLLSKYDPEEPIYFGRRFKPYVKQGYMS 208

  Fly   206 GGAGYVLSKMALHRLIKLGFSNSSICTNRNYGYEDVELGRCLAGVGVVGGDSRDEQGLSRFIPFS 270
            |||||||||.||.|.:. .|.... ||:.: ..||:.||||:..:.|..|||||..|...|.||.
Human   209 GGAGYVLSKEALKRFVD-AFKTDK-CTHSS-SIEDLALGRCMEIMNVEAGDSRDTIGKETFHPFV 270

  Fly   271 PLH----WYPQPPDWYQPLLYYTSPDNSSDCCSNTAISFHYNNAQEFYVLEYIIYKLRIFG-INR 330
            |.|    .|.....||....|| .|.....|||:.|:||||.::...|.|||::|.||.:| :.|
Human   271 PEHHLIKGYLPRTFWYWNYNYY-PPVEGPGCCSDLAVSFHYVDSTTMYELEYLVYHLRPYGYLYR 334

  Fly   331 ELGPLPKK--KASSRPMSINLQTTKEENGHIAL 361
            ....||::  |..|       |..|.|:..:.|
Human   335 YQPTLPERILKEIS-------QANKNEDTKVKL 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2975	NP_608719.1	Galactosyl_T	90..>214	CDD:304462	63/123 (51%)
C1GALT1	NP_064541.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	41..72
C1GALT1	NP_064541.1	Galactosyl_T	107..>221	CDD:328824	61/113 (54%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2246
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1407357at2759
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103571
Panther	1	1.100	-	-	O	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.780