DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2975 and CG8708

DIOPT Version :9

Sequence 1:	NP_608719.1	Gene:	CG2975 / 33481	FlyBaseID:	FBgn0031468	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_610360.2	Gene:	CG8708 / 35792	FlyBaseID:	FBgn0033271	Length:	450	Species:	Drosophila melanogaster

Alignment Length:	342	Identity:	149/342 - (43%)
Similarity:	199/342 - (58%)	Gaps:	17/342 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RKRLELMLMLLIGLAWGILLSELMKRTRWQNHADRLKEESSPFPSSQRSRNLRTPPTIAPSTTNP 71
            |.:...:..|:.||..|..|:::....  ..|.......|..|..||    :.|...:||..:..
  Fly    17 RSKNRSVFTLIAGLVVGYCLAQIFSSI--APHESLYPYLSRRFSDSQ----VATGGQLAPEQSGL 75

  Fly    72 PPD------ILAARLFNETRVLCMVLTSPKTHHTRAIHIKRTWGRRCNKLIFMSTKADKELGSVA 130
            ..|      .:|.:|..|.|:||.|:|:|..|..:|.|:|||||:|||.|:|||:.||:||.:|.
  Fly    76 KHDHRNDNVSVAEQLKKEVRILCWVMTNPTNHKKKARHVKRTWGKRCNILLFMSSGADEELPTVK 140

  Fly   131 LNVREGYSNLWPKTRAALQYVYKHHFQKYDWFLKADDDTYFIMENLRAFLHAHNFREPVYFGNKF 195
            |:|.||..|||.|.:.|.:|||.||:...|:|.|||||||.::||:|..|:.:|...||:||.||
  Fly   141 LDVGEGRENLWAKVKEAFKYVYHHHYNDADFFYKADDDTYAVIENMRYMLYPYNPETPVHFGFKF 205

  Fly   196 RQHVKEGYMSGGAGYVLSKMALHRLIKLGFSNSSICTNRNYGYEDVELGRCLAGVGVVGGDSRDE 260
            :..||:|||||||||:||:.||.|.:..|..|..:|.......||:|:|||:..:.|..||||||
  Fly   206 KPFVKQGYMSGGAGYILSREALRRFVVEGIPNPKMCLPGTVVNEDIEIGRCMENLNVTAGDSRDE 270

  Fly   261 QGLSRFIPFSP-LHWYPQPPD---WYQPLLYYTSPDNSSDCCSNTAISFHYNNAQEFYVLEYIIY 321
            .|..|..||.| .|..|...|   ||...|||.: |:..||||:.||||||.....||||:|:||
  Fly   271 IGRGRMFPFIPEHHLIPAKADKNFWYWNYLYYKT-DDGLDCCSDLAISFHYVAPNSFYVLDYLIY 334

  Fly   322 KLRIFGINRELGPLPKK 338
            .|:.:|:.|.|.|||.|
  Fly   335 HLKPYGLLRSLEPLPAK 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2975	NP_608719.1	Galactosyl_T	90..>214	CDD:304462	69/123 (56%)
CG8708	NP_610360.2	MIP-T3	<385..>449	CDD:287245
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45458847
Domainoid	1	1.000	173	1.000	Domainoid score	I3636
eggNOG	1	0.900	-	-		E1_KOG2246
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D103727at6656
OrthoFinder	1	1.000	-	-		FOG0000473
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103571
Panther	1	1.100	-	-	P	PTHR23033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	8	7.750