DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3119 and B3GLCT

DIOPT Version :9

Sequence 1:	NP_608717.2	Gene:	CG3119 / 33479	FlyBaseID:	FBgn0031466	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_919299.3	Gene:	B3GLCT / 145173	HGNCID:	20207	Length:	498	Species:	Homo sapiens

Alignment Length:	215	Identity:	55/215 - (25%)
Similarity:	88/215 - (40%)	Gaps:	47/215 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 ILCMVLTCPENVQSLARSVYETWGQRCSRLIFASSEDYEPLGVVGV---VEPTGGGY-------- 116
            |...|.||.:........|.:||..:.|.:.:.|  ||....:..|   :..|..|:
Human   269 IFVAVKTCKKFHGDRIPIVKQTWESQASLIEYYS--DYTENSIPTVDLGIPNTDRGHCGKTFAIL 331

  Fly   117 EDLWNKTREGFRHVWEHYAGDYDWFLKADDDTYVVMENLQHLLRGFDPNTPVF----FGYKMSRY 177
            |...|::::           ...|.:..||||.:.:..|||||..:|...|||    :||.:...
Human   332 ERFLNRSQD-----------KTAWLVIVDDDTLISISRLQHLLSCYDSGEPVFLGERYGYGLGTG 385

  Fly   178 NVSYMSGGASYILSREALHRFAT---QAYESEVICPQPKKMGIEDFYMGICMQNVGVHFVDSTHA 239
            ..||::||...:.||||:.|...   :.|.::.    |     :|..:|:|...:|   :..||:
Human   386 GYSYITGGGGMVFSREAVRRLLASKCRCYSNDA----P-----DDMVLGMCFSGLG---IPVTHS 438

  Fly   240 -LDGDTKPKFMPLDLENYMS 258
             |....:|...|.|   |:|
Human   439 PLFHQARPVDYPKD---YLS 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3119	NP_608717.2	Galactosyl_T	86..235	CDD:304462	40/166 (24%)
B3GLCT	NP_919299.3	Galactosyl_T	264..467	CDD:304462	55/215 (26%)
B3GLCT	NP_919299.3	Prevents secretion from ER	495..498
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2246
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810