Protein Alignment Duox and cybb

DIOPT Version :9

• Sequence 1: NP_001259968.1
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_001025689.1
• Gene: cybb / 595081
• XenbaseID: XB-GENE-978453
• Length: 570
• Species: Xenopus tropicalis
• Alignment Length: 585
• Identity: 160/585 - (27%)
• Similarity: 259/585 - (44%)
• Gaps: 118/585 - (20%)

  Fly  1032 YLFL-FYVVTIVLFVERFIHYSFMAEHTDLRHIMGVGIAITRGSAASLSFCYSLLLLTMSRNLIT 1095
            |||. ||:|           |....::...|.:.|..:|..|..||.|:|...|:||.:.|||::
 Frog    24 YLFWNFYLV-----------YDEGEKYFYSRKLYGSALAWARAPAACLNFNCLLILLPVCRNLLS 77

  Fly  1096 KLKEFPI-------QQYIPLDSHIQFHKIAACTALFFSVLHTVGHIVNFYH-VSTQSHEN---LR 1149
            .|:....       :|   ||.::.|||:.|......:.:||..|:.|... |..:...|   ..
 Frog    78 FLRGSSACCGRSLRRQ---LDRNLTFHKMVAWMIALHTAIHTGAHLFNVERLVDARVEANGTIQA 139

  Fly  1150 CLT----RE----VHFASDYKPD--------ITFWLFQTVTGTTGVMLFIIMCIIFVFAHPTIRK 1198
            .||    ||    ::|.....|:        .||     :.|.|||::.:.:.:|...:..|||:
 Frog   140 ALTDLGDREGESYLNFVRSRVPNPIGGINVAFTF-----LAGLTGVVITLALILIITSSTKTIRR 199

  Fly  1199 KAYNFFWNMHTLYIGLYLLSLIHGLARLT------------------------------------ 1227
            ..:..||..|.|::..::..:|||..::.
 Frog   200 SYFEVFWYTHHLFVIFFIGLVIHGAGKIVRGQTDKSLEKHNSTECEDKFTEWGNITSCPIPQFAG 264

  Fly  1228 GPPRFWMFFLGPGIVYTLDKIVSLRTKYMALDVIDTDLLPSDVIKIKFYRPPNLKYLSGQWVRLS 1292
            ..|..|.:.:.|.::|..:::|........:.:......|...|:::. :....|...||::.:.
 Frog   265 NEPMTWKWVVAPMVLYVFERLVRFWRSQQKVVITKVVTHPFKTIELQM-KMKGFKMEVGQYIFVQ 328

  Fly  1293 CTAFRPHEMHSFTLTSAPHENFLSCHIKAQGPWTWKLRNYFDPCNYNPED------QPKIRIEGP 1351
            |.|....|.|.|||||||.|:|.|.||:..|.||   ...|..|..:..:      .|||.::||
 Frog   329 CPAVSKLEWHPFTLTSAPEEDFFSIHIRIVGDWT---EGLFKACGCDKTEFQDAWKMPKIAVDGP 390

  Fly  1352 FGGGNQDWYKFEVAVMVGGGIGVTPYASILNDLVFGTSTNRYSGVACKKVYFLWICPSHKHFEWF 1416
            ||..::|.:.:|||::||.||||||:||:|.. |:....|..|.:..||:||.|:|...:.||||
 Frog   391 FGTASEDVFSYEVAMLVGAGIGVTPFASVLKS-VWYRYVNDASTLRLKKIYFYWLCRDTQAFEWF 454

  Fly  1417 IDVLRDVE----KKDVTNVLEIHIFITQFFHK----FDLRTTMLYICENHFQRLSKTSIFTGLKA 1473
            .|:|:.:|    ::|..|.|..:|::|.:...    |.|         :|.|   :..:.||||.
 Frog   455 ADLLQSLETQMQERDNANFLVYNIYLTGWDESQATAFSL---------HHDQ---EKDVITGLKQ 507

  Fly  1474 VNHFGRPDMSSFLKFVQKKHSYVSKIGVFSCGPRPLTKSV--MSACDEVNKTRKLPYFIHHFENF 1536
            ...:|||:..:..|.:...|: .|::|||.|||..|.:::  .|..:.....|.: :||.:.|||
 Frog   508 KTLYGRPNWENEFKTIANAHT-SSRVGVFLCGPESLAETLNKQSIANSTVDPRGV-HFIFNKENF 570

  Fly  1537  1536
             Frog   571  570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duox	NP_001259968.1	An_peroxidase	70..580	CDD:281139
		dual_peroxidase_like	72..625	CDD:188652
		EFh	827..882	CDD:238008
		EFh	860..921	CDD:238008
		EF-hand_7	860..920	CDD:290234
		EFh	895..966	CDD:238008
		EF-hand_7	899..965	CDD:290234
		Ferric_reduct	1084..1217	CDD:280043	40/159 (25%)
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783	95/286 (33%)
cybb	NP_001025689.1	Ferric_reduct	65..219	CDD:366815	40/161 (25%)
		NOX_Duox_like_FAD_NADP	297..570	CDD:99783	95/291 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000155
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X184
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910