Protein Alignment Duox and Irc

DIOPT Version :10

• Sequence 1: NP_608715.2
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 134/565 - (23%)
• Similarity: 214/565 - (37%)
• Gaps: 149/565 - (26%)

  Fly    56 SVHCYEKMYSQTEKQRYDGWYNNLAHPDWGSVDSHLVRKAPPSYSDGVYAMAGANRPSTRRLSRL 120
            |...||..:.|..||:.....:|||.|.|.....|                 ..::|.::.:|
  Fly   187 SKELYEPDHIQISKQQTFESNSNLALPQWAQFVEH-----------------DLSKPVSQSMS-- 232

  Fly   121 FMRGKDGLGSKFNRTALLAFFGQLVANEIVMASESGCPIE-MHRIEIEKCDEMYDRECR------ 178
                                              :|.||| ..|.:|......:...|.
  Fly   233 ----------------------------------NGAPIECCSRDQINLQPRHHHPACAPILYQP 263

  Fly   179 GDKY-IP----FHRAAY---DRDTGQSPNAPREQINQMTAWIDGSFIYSTSEAWLNAMRSFHNGT 235
            |.|| :|    :.|:|.   |.:.|.:     ||:||.|..:|.|.:|..:.|....:|....|.
  Fly   264 GGKYDVPSCLNYVRSALAVADCNFGGA-----EQLNQATGSLDLSQLYGFTAAAERKLRVLEGGL 323

  Fly   236 LLTEKDGK-----LPVRNTMRVPLFNNPVPSVMKMLSPERLFLLGDPRTNQNPAILSFAILFLRW 295
            |.:...|:     ||:......|.|     .....:.....|..||.|.|.:|..:....:|:|.
  Fly   324 LRSTPRGEFDNALLPIATDTEGPSF-----CARATIGDGTCFAAGDSRVNSSPFSILIYTIFMRN 383

  Fly   296 HNTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFLGTSLPPYEGYKQDIHPG--- 357
            ||.:|..:|:.:|.||||.::|.|:...:...:.|::.|:||..||..:......||   |.
  Fly   384 HNKVAAELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLGQKMSSEIRRKQ---PNRAL 445

  Fly   358 -IGHIFQAAAFRFGHTMIPPGIY-----------RRDGQCNF--KETP----------MGYPAVR 398
             :.:.|..||.||..:|:|..:.           .::.|..|  ||.|          :..|.::
  Fly   446 EVSNEFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNNQYVFISKELPTKNLFELKEEIYKPKLQ 510

  Fly   399 LCSTWWDSSGFFADTSVEEVLMGLASQISEREDPVLCSDV---RDKLFGPMEFTRRDLGALNIMR 460
                       :....:..:|..|.:|.:.:.|......|   :|     .:.|..|:.|.:|.|
  Fly   511 -----------YTSQKLNNILESLLNQETMKMDAAYSGGVVWHKD-----TKPTHADILAFDIQR 559

  Fly   461 GRDNGLPDYNTARESYGLKRH-KTWTDINPPLFE--TQPELLDMLKEAYDNKLDDVDVYVGGMLE 522
            |||:||..|....||..|.|. ::|.|     ||  ...::||.||..|.: ..|||:.|||:.|
  Fly   560 GRDHGLLPYYRYLESCVLSRPVESWKD-----FEHFIPSDVLDKLKTIYAS-WADVDLIVGGISE 618

  Fly   523 S--YGQPGEFFTAVIKEQFQRLRDADRFWFENERNGIFTPEEIAE 565
            :  :|..|..|:.:|.|||..:..      :|::..:....|:.|
  Fly   619 NPVHGSIGPTFSCIISEQFVHVLK------QNQQKAVQKHTELVE 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duox	NP_608715.2	dual_peroxidase_like	72..625	CDD:188652	128/549 (23%)
		PTZ00184	807..965	CDD:185504
		EFh	860..921	CDD:238008
		PLN02844	<1081..>1393	CDD:215453
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	134/565 (24%)