Protein Alignment Duox and cybb

DIOPT Version :9

• Sequence 1: NP_001259968.1
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_956708.1
• Gene: cybb / 393386
• ZFINID: ZDB-GENE-040426-1380
• Length: 565
• Species: Danio rerio
• Alignment Length: 579
• Identity: 154/579 - (26%)
• Similarity: 271/579 - (46%)
• Gaps: 95/579 - (16%)

  Fly  1029 NIFYLFLFYVVTIVLFVERFIHYSFMAE-HTDLRHIMGVGIAITRGSAASLSFCYSLLLLTMSRN 1092
            ::|.:.::..:.:.|||  :.:.:|:.: :...|.|:|..::..|..||.|:|...|:||.:.||
Zfish    11 SVFVILVWLGINVFLFV--YFYLAFLIDKYYYTRVILGHALSWARAPAACLNFNCMLILLPVCRN 73

  Fly  1093 LITKLK-------EFPIQQYIPLDSHIQFHKIAACTALFFSVLHTVGHIVNF------------- 1137
            |::.|:       ....:|   ||.:|.|||:.|....|.:.:|.:.|:.||
Zfish    74 LLSFLRGSIQCCSRTAARQ---LDRNITFHKLVAYMIAFHTAVHIIAHLFNFERFMDSQLMINSS 135

  Fly  1138 ---YHVSTQSHENLRCLTREVHFASDYKPDITFWLFQTVTGTTGVMLFIIMCIIFVFAHPTIRKK 1199
               |.:|...:.:.|.....:. ::|..|.|.  :|.||.|.|||::.:.:.:|...:...||:.
Zfish   136 HLPYVLSQIGNNDNRSYLNPIR-SNDTNPTIV--MFTTVAGLTGVVITLALILIITSSMEVIRRS 197

  Fly  1200 AYNFFWNMHTLYIGLYLLSLIHGLARLT------------------------------------- 1227
            .:..||..|.|:|..::..::||:.|:.
Zfish   198 YFEVFWFTHHLFIVFFIGLVLHGIGRIVRGQTDADLQVHDPTICHSKFEKWGQNVTDCPVPIFAG 262

  Fly  1228 GPPRFWMFFLGPGIVYTLDKIVSLRTKYMALDVIDTDLLPSDVIKIKFYRPPNLKYLSGQWVRLS 1292
            .||:.|.:.:||..:|..:::|........:.:......||..::::. :....|...||::.:.
Zfish   263 NPPKTWKWVVGPMFLYVCERLVRFYRSQQKVVITKVVTHPSKTLELQM-KKKGFKMEVGQYIFMM 326

  Fly  1293 CTAFRPHEMHSFTLTSAPHENFLSCHIKAQGPWTWKLRNYFDPCN------YNPEDQPKIRIEGP 1351
            |.:....|.|.|||||||.|:..|.||:..|.||..|   :..|.      .:....||:.::||
Zfish   327 CPSISQLEWHPFTLTSAPEEDHFSVHIRIVGDWTQAL---YSACGGDKTAVLDAWTLPKMAVDGP 388

  Fly  1352 FGGGNQDWYKFEVAVMVGGGIGVTPYASILNDLVFGTSTNRYSGVACKKVYFLWICPSHKHFEWF 1416
            ||..::|.:::|..::||.||||||:||:|.. |:.........|..||:||.|:||..:.||||
Zfish   389 FGTASEDVFRYEAVMLVGAGIGVTPFASVLKS-VWYKHVQENQNVFTKKIYFYWLCPETQAFEWF 452

  Fly  1417 IDVLRDVEK----KDVTNVLEIHIFITQFFHKFDLRTTMLYICENHFQRLSKTSIFTGLKAVNHF 1477
            .|:|:.:||    |::::.|..:|::|::   .|.....|.:     |..::....||||....:
Zfish   453 ADLLQSLEKQMSDKNMSDFLSYNIYLTRW---KDAEAAHLRV-----QYEAEDDPITGLKQKTRY 509

  Fly  1478 GRPDMSSFLKFVQKKHSYVSKIGVFSCGPRPLTKSVMSACDEVNKTRKLPYFIHHFENF 1536
            |:|:..:....:..:|. .:|:|||.|||..|.|::...|  ::.|.....||.:.|||
Zfish   510 GKPNWDNEFSLIASQHP-GTKVGVFLCGPTALGKALSKQC--LSHTEGGTEFIFNKENF 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duox	NP_001259968.1	An_peroxidase	70..580	CDD:281139
		dual_peroxidase_like	72..625	CDD:188652
		EFh	827..882	CDD:238008
		EFh	860..921	CDD:238008
		EF-hand_7	860..920	CDD:290234
		EFh	895..966	CDD:238008
		EF-hand_7	899..965	CDD:290234
		Ferric_reduct	1084..1217	CDD:280043	41/155 (26%)
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783	88/280 (31%)
cybb	NP_956708.1	Ferric_reduct	56..216	CDD:280043	45/165 (27%)
		NOX_Duox_like_FAD_NADP	295..565	CDD:99783	88/285 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000155
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100242
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X184
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810