Protein Alignment Duox and Pxd

DIOPT Version :9

• Sequence 1: NP_001259968.1
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_001163633.1
• Gene: Pxd / 2768671
• FlyBaseID: FBgn0004577
• Length: 690
• Species: Drosophila melanogaster
• Alignment Length: 629
• Identity: 171/629 - (27%)
• Similarity: 270/629 - (42%)
• Gaps: 104/629 - (16%)

  Fly    49 SYGLEL---GSVHCY--EKMYSQTEKQRYDGWYNNLAHPDWGSVDSHLVRKAPPSYSDGVYA--- 105
            :||...   |.|.|.  ..:..:|..:..||..|:|..|..|..:|...|...|.|:||:.|
  Fly    80 AYGYSFPTAGRVSCAAPPAVCEKTAYRTLDGSCNHLEQPGLGVANSKYGRLLTPKYADGISAPTR 144

  Fly   106 -MAGANRPSTRRLSRLFMRGKDGLGSKFNRTALLAFFGQLVANEIVMASESGCPIEMH------- 162
             :.|...||.|.:|.:....:|....:|  |.....:||::.:::.|.: .|...:.|
  Fly   145 SVTGDELPSARLVSLVAFGEQDVPDPEF--TLHNMQWGQIMTHDMSMQA-GGTQSKKHPTRCCTD 206

  Fly   163 ---------------RIEIEKCDEMYDRECRGDKYIPFHRAAYDRDTG-QSPNAPREQINQMTAW 211
                           .|.:...|..|.:.  |.:.:.|.|...|||:. |....|.||:..:|::
  Fly   207 DGRLIGLDTAHKTCFAIIVPPHDPAYSQV--GTECLNFVRTLTDRDSNCQYQGGPAEQLTVVTSY 269

  Fly   212 IDGSFIYSTSEAWLNAMRSFHNGTLLTEKDGKLPVRNTMR-VPLFNNPVPSVMKMLSPERLFLLG 275
            :|.|.:|..|....:.:|.|..|.::.|:      ||..: :||..|.......:.:.|..:..|
  Fly   270 LDLSLVYGNSIQQNSDIREFQGGRMIVEE------RNGAKWLPLSRNVTGDCDAVDASEVCYRSG 328

  Fly   276 DPRTNQNPAILSFAILFLRWHNTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFL 340
            |.|.||||.:.....:.||.||.:|..:..::|.:.|..::|.||...||..|.:..||:||.||
  Fly   329 DVRVNQNPGLAILQTILLREHNRIADALSALNPHYDDRTLFQEARKINIAQYQQISYYEWLPIFL 393

  Fly   341 GTS---------LPPYEGYKQD----IHPGIGHIFQAAAFRFGHTMIPPGIYRRDGQCNFKETPM 392
            |..         ..|...|..|    |.|.:.:....||||:.|:.|       :|:.:......
  Fly   394 GGENMLKNRLIYKAPSGSYINDFDPNIDPSVLNEHATAAFRYFHSQI-------EGRLDLLSELR 451

  Fly   393 GYPAVRLCSTWWDSSGFF-ADTSVEEVLMGLASQISEREDPVLCSDVRDKLFGPMEFTRR----- 451
            ........|.|::..|.. ...:.:.:..|.|:|..|..|......::..||      ||
  Fly   452 QVLGSLTLSDWFNRPGIIEVGDNFDSLTRGHATQPEELTDINFDRQIKHFLF------RRNMPFG 510

  Fly   452 -DLGALNIMRGRDNGLPDYNTARESYGLKRHKTWTD----INPPLFETQPELLDMLKEAYDNKLD 511
             ||.:|:|.|.||:||..||..||..||:|..:|..    |:||       :|:.||..|.:. :
  Fly   511 SDLRSLDIQRNRDHGLASYNDMREFCGLRRAHSWEGYGDLISPP-------ILEKLKSLYPSH-E 567

  Fly   512 DVDVYVGGMLESY---GQPGEFFTAVIKEQFQRLRDADRFWFEN-ERNGIFTPEEIAELRKITLW 572
            |||:.||..||::   ...|..|..::.|||.|.|..|||:||| ::...|||:::.||||.::.
  Fly   568 DVDLTVGASLEAHVAGALAGPTFLCILTEQFYRTRVGDRFFFENGDKLTGFTPDQLEELRKASMA 632

  Fly   573 DIIV-NSTDVKEEEIQKDVFMWRTGD------PCPQPMQLNATE 609
            .::. |...:  ..:|.:.|  ||..      ||....|::.|:
  Fly   633 RLLCDNGNHI--SSMQPEAF--RTVSHSNPIIPCSNIPQVDLTK 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duox	NP_001259968.1	An_peroxidase	70..580	CDD:281139	157/566 (28%)
		dual_peroxidase_like	72..625	CDD:188652	165/601 (27%)
		EFh	827..882	CDD:238008
		EFh	860..921	CDD:238008
		EF-hand_7	860..920	CDD:290234
		EFh	895..966	CDD:238008
		EF-hand_7	899..965	CDD:290234
		Ferric_reduct	1084..1217	CDD:280043
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783
Pxd	NP_001163633.1	An_peroxidase	105..643	CDD:281139	157/571 (27%)
		peroxinectin_like	260..638	CDD:188655	119/404 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.910