Protein Alignment Duox and frp1

DIOPT Version :9

• Sequence 1: NP_001259968.1
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_595065.1
• Gene: frp1 / 2539711
• PomBaseID: SPBC1683.09c
• Length: 564
• Species: Schizosaccharomyces pombe
• Alignment Length: 586
• Identity: 110/586 - (18%)
• Similarity: 213/586 - (36%)
• Gaps: 127/586 - (21%)

  Fly  1006 DKPRHWLLAKWDAYITFLEENRQNIFYLFLFYVVTIVLFVERFIHYSF--------MAEHTDLRH 1062
            ||.:.||    :.|..|:   ||...||....|:..::.|......|.        .:.|.....
pombe    48 DKRQIWL----EKYYLFV---RQIYTYLVTHKVILTLIAVPVVFAISIPFIGMQTPASSHGKQTT 105

  Fly  1063 IMGVGIAITRGSAASLSFCYSLLLLTMSRNLITKLKEFPIQQYIPLDSHIQF---HKIAACTALF 1124
            .:..|.......||.|.|....|.:|   :....:|..|....: :.||.:.   |:..:..|:.
pombe   106 QVSTGNWSKNAVAARLGFLACGLYVT---SYFFSIKNNPFALLL-ISSHEKMNYVHRRLSQYAIM 166

  Fly  1125 FSVLHTVGHIVNFYHVSTQSHENLRCLTREVHFASDYKPDITFWLFQTVTGTTGVMLFIIMCIIF 1189
            ...:|      .|.::...:......||..|                |:   .|.::..:|.|:.
pombe   167 IGAIH------GFAYIGLAAQGKRALLTARV----------------TI---IGYVILGLMVIMI 206

  Fly  1190 VFAHPTIRKKAYNFFWNMHTL-YIGLYLLSLIHGLARLTGPPRFWMFFLGPGI-VYTLDKIVSLR 1252
            |.:.|..|::.|.:|:.:|.: .||..:...:|        .|..:.::...: ||..|:...:.
pombe   207 VSSLPFFRRRFYEWFFVLHHMCSIGFLITIWLH--------HRRCVVYMKVCVAVYVFDRGCRML 263

  Fly  1253 TKYMALDVIDTDLLPSDVIKIKFYRPP----NLKYLSGQWVRLSCTAFRPHEMHSFTLTSAPHEN 1313
            ..::.....|..|:..|:|.:|..||.    .|.:.:|..:.::..:....::|.||:.|.|.::
pombe   264 RSFLNRSKFDVVLVEDDLIYMKGPRPKKSFFGLPWGAGNHMYINIPSLSYWQIHPFTIASVPSDD 328

  Fly  1314 FLSCHIKAQGPWTWKL------RNYFDPCNYNPEDQP---------------------------- 1344
            |:...:..:..:|.:|      ::..|..:.|..|:.
pombe   329 FIELFVAVRAGFTKRLAKKVSSKSLSDVSDINISDEKIEKNGDVGIEVMERHSLSQEDLVFESSA 393

  Fly  1345 ---KIRIEGPFGGGNQDWYKFEVAVMVGGGIGVTPYASILNDLVFGTSTNRYSGVACKKVYFLWI 1406
               .:.::||:|..:..:..:....:..||:||:....|:.|.:...|...:       :.|:|.
pombe   394 AKVSVLMDGPYGPVSNPYKDYSYLFLFAGGVGVSYILPIILDTIKKQSRTVH-------ITFVWS 451

  Fly  1407 CPSHKHFEWFIDVLRDVEKK--DVTNVLEIHIFITQFFHKFDLRTTMLYICENHFQRLSKTSIFT 1469
            ..|..       :|..|.|.  :.....|::|.|  |.|     .|..|..|......|:::...
pombe   452 ARSSA-------LLNIVHKSLCEAVRYTEMNINI--FCH-----LTNSYPVEEVSSLNSQSARNY 502

  Fly  1470 GLKAVNHFGRPDMSSFLK-FVQKKHSYVSKIGVFSCGPRPLTKSVMSACDEVNKTRKLPYFIHHF 1533
            .|:.:|  ||||::.:.| |:....:..:.:.  |||...|.:.:.| |...:....:..:.|:.
pombe   503 SLQYLN--GRPDVNDYFKDFLHATGTQTAALA--SCGSDKLLRHLKS-CVNTHSPSTVDLYQHYE 562

  Fly  1534 E 1534
            |
pombe   563 E 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duox	NP_001259968.1	An_peroxidase	70..580	CDD:281139
		dual_peroxidase_like	72..625	CDD:188652
		EFh	827..882	CDD:238008
		EFh	860..921	CDD:238008
		EF-hand_7	860..920	CDD:290234
		EFh	895..966	CDD:238008
		EF-hand_7	899..965	CDD:290234
		Ferric_reduct	1084..1217	CDD:280043	25/136 (18%)
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783	60/314 (19%)
frp1	NP_595065.1	Ferric_reduct	124..235	CDD:280043	25/139 (18%)
		NOX_Duox_like_FAD_NADP	279..480	CDD:99783	37/216 (17%)
		NAD_binding_6	414..547	CDD:285298	35/158 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0039
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000155
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100242
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R458
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740