Protein Alignment Duox and hpx-2

DIOPT Version :9

• Sequence 1: NP_001259968.1
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: NP_506432.1
• Gene: hpx-2 / 179880
• WormBaseID: WBGene00008627
• Length: 718
• Species: Caenorhabditis elegans
• Alignment Length: 601
• Identity: 168/601 - (27%)
• Similarity: 267/601 - (44%)
• Gaps: 109/601 - (18%)

  Fly    57 VHCYEKMYSQTEKQRYDGWYNNLAHPDWGSVDSHLVR-KAPPSYSDGV-----YAMAGANRPSTR 115
            ::|..:.:  |..:...|..||..:.|.|:..|.|.| ....||:||:     .::.|...||.|
 Worm   147 INCNNRFH--TSIRSITGLCNNRQNSDLGNSVSPLRRILGAASYADGLGRIRTRSVNGGELPSAR 209

  Fly   116 RLSRLFM--RGKDGLGSKFNRTALLAFFGQLVANEIV-----MASESGCPIEMHRIEIEKCD--E 171
            .:|....  |.........|...::  .||.:|:::|     :|.:.|.      ::...|:  :
 Worm   210 LISNRIHDDRNNQVFSPSINHLHMI--IGQFIAHDVVFMPSSVARDGGA------LDCSACNSPQ 266

  Fly   172 MYDREC------RGDKY-----IPFHRAAYDRDTGQSPNAPREQINQMTAWIDGSFIYSTSEAWL 225
            .....|      |.|.|     :...||.    .||.....|.||.|.:.::|.|.:|.:::...
 Worm   267 RVSPNCAPITIPRNDPYFNTPCMRLTRAL----NGQENFGVRSQIGQNSHFLDLSPVYGSADCEA 327

  Fly   226 NAMRSFHNGTLLTEKD--GKLPVRNTMRVPLFNNPVPSVMKMLSPERLFLLGDPRTNQNPAILSF 288
            ..:|||..|.:||..|  ..||.:|.      |:   |..:..:|...|..||.|.:.:||::..
 Worm   328 ETVRSFQEGKMLTFDDLGYTLPPQNA------ND---SNCQSSAPFHCFTCGDFRNSLHPALIPV 383

  Fly   289 AILFLRWHNTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFL------GTSLPP- 346
            ..:.::.||.||::::...|.::||.|:|..|..:|...|:::..||:|.:|      ..:|.|
 Worm   384 HTILIKEHNRLAEQVRVARPRFNDEQIFQLVRKIMIGMWQHIVYNEYIPKYLPRRTIRNFALRPL 448

  Fly   347 ----YEGYKQDIHPGIGHIFQAAAFRFGHTMIPPGIYRRDGQCNF---KETPMGYPAVRLCSTWW 404
                :.||...:.|.|...|..|||||||:           |..|   :.|..|.||..     :
 Worm   449 RNGVHRGYSTSVDPSISAEFAGAAFRFGHS-----------QSRFDFPRLTENGRPAGN-----Y 497

  Fly   405 DSSG--FFAD----TSV---EEVLMGLASQISEREDPVLCSDVRDKLFGPMEFTRR-----DLGA 455
            |...  |:||    |.:   |.|:.|:....:.:.|......:|:::|   |...|     ||.:
 Worm   498 DLGNDIFYADQMYLTRIGGWEPVMNGMVRMPAMKSDRYFSFGIRNQMF---EIRGRNGSGVDLVS 559

  Fly   456 LNIMRGRDNGLPDYNTARESYGLKRHKTWTDINPPLFETQPELLDMLKEAYDNKLDDVDVYVGGM 520
            :||.||||.||..|...|:..||....::.::|....:   |.:..|:..|.:.. |:|:|||.|
 Worm   560 INIQRGRDMGLFPYIQYRQLVGLPTVTSFNELNTTFSQ---ENIQALRNVYSDPA-DIDLYVGIM 620

  Fly   521 LE---SYGQPGEFFTAVIKEQFQRLRDADRFWFENERNGI--FTPEEIAELR-KITLWDIIVNST 579
            ||   |.||.|...:.:|.|||:.|:..|||::|:...|.  ||.|||:||| |.:|..||..:.
 Worm   621 LEEPLSGGQLGPTASFMIGEQFRALKRGDRFFYESIAEGTDNFTQEEISELRNKTSLAKIICTNM 685

  Fly   580 DVKEEEIQKDVFMWRT 595
            |. ...|..|:|..|:
 Worm   686 DF-AARINTDIFDHRS 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duox	NP_001259968.1	An_peroxidase	70..580	CDD:281139	161/571 (28%)
		dual_peroxidase_like	72..625	CDD:188652	166/586 (28%)
		EFh	827..882	CDD:238008
		EFh	860..921	CDD:238008
		EF-hand_7	860..920	CDD:290234
		EFh	895..966	CDD:238008
		EF-hand_7	899..965	CDD:290234
		Ferric_reduct	1084..1217	CDD:280043
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783
hpx-2	NP_506432.1	An_peroxidase	158..696	CDD:376988	164/582 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910