Protein Alignment Duox and LOC1277631

DIOPT Version :10

• Sequence 1: NP_608715.2
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: XP_061516638.1
• Gene: LOC1277631 / 1277631
• VectorBaseID: AGAMI1_011985
• Length: 1410
• Species: Anopheles gambiae
• Alignment Length: 682
• Identity: 193/682 - (28%)
• Similarity: 294/682 - (43%)
• Gaps: 144/682 - (21%)

  Fly    77 NNLAHPDWGSVDSHLVRKAPPSYSDGV-----YAMAGANRPSTRRLSRLFMRGKDGLGSKFNRTA 136
            |||.:|:.|...:...|..||.|.||:     .::.||..|:.|.:|.|.......|.:::  :.
Mosquito   729 NNLRNPELGQSLTVFARLLPPVYDDGISQPRSLSVTGAPLPNPRSISSLIHPDISNLHTRY--SL 791

  Fly   137 LLAFFGQLVANEIVMASESGCPIE--MHRIEIEKCDEMYDRECRGDKYI-----PFHRAAYDRD- 193
            ::..:.|.:.:::.|.     ||.  .|. .|..|     |.|...:.:     ||  ....||
Mosquito   792 MVMQYAQFLDHDLTMT-----PIHKGFHE-SIPSC-----RSCDSPRTVHPECSPF--PVPPRDH 843

  Fly   194 ---------------------TGQSPNAPREQINQMTAWIDGSFIYSTSEAWLNAMRSFHNGTLL 237
                                 .||....|||||||.||::|.|.||..:......:|.|
Mosquito   844 YYPEVNVTSGERLCFPSMRSLPGQQTLGPREQINQNTAFLDASQIYGENGCIAKKLRGF------ 902

  Fly   238 TEKDGKL-----PVRNTMRVPLFNNPVPSVMKMLSPE-RLFLLGDPRTNQNPAILSFAILFLRWH 296
               .|:|     |::....:|  .:||....|  ||. ..|:.||.|.::.|.:.:...:|:|.|
Mosquito   903 ---SGRLNSTIHPIQGKELLP--QSPVHPECK--SPSGYCFIAGDGRASEQPGLTAIHTVFMREH 960

  Fly   297 NTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFL--------GTSLPP---YEGY 350
            |.:.:.::.|:|.|:.:.:|::||..|||..|::...|:||..|        |..|..   |:.|
Mosquito   961 NRIVEGLRGVNPHWNGDQLYEQARRIVIAQNQHITYNEFLPRILSWNAVNLYGLKLLAQGYYKEY 1025

  Fly   351 KQDIHPGIGHIFQAAAFRFGHTMIPPGIYRRDGQCNFKETPMGYPAVRLCSTWWDSSGFFADTSV 415
            ....:|.|...|..||||.||:::.|.|.|    .:.:..|:. |.:.|...::.:..|.....|
Mosquito  1026 NPTCNPSIVTEFATAAFRIGHSLLRPHIPR----LSVQHQPID-PPLLLRDGFFRTDNFLQPGLV 1085

  Fly   416 EEVLMGLASQISEREDPVLCSDVRDKLFGP--MEFTRRDLGALNIMRGRDNGLPDYNTARESYGL 478
            :|:..||.:...|..|..:..:|.:.||..  :.|:..||.||||.||||:|:|.||..|....|
Mosquito  1086 DEISRGLVATPMETLDQFITGEVTNHLFEDRRIPFSGFDLIALNIHRGRDHGMPSYNNYRALCNL 1150

  Fly   479 KRHKTWTDINPPLFETQPELLDMLKEAYDNKLDDVDVYVGGMLE---SYGQPGEFFTAVIKEQFQ 540
            ||.:||.|:..   |..||::..|:..|.: :||:|::.|||.|   ..|..|..|..:|..||:
Mosquito  1151 KRAQTWEDLGR---EIPPEVIARLRRIYAH-VDDIDLFPGGMSERPLQGGLVGPTFACIIAIQFR 1211

  Fly   541 RLRDADRFWFENERNGI-FTPEEIAELRKITLWDIIVNSTDVKEEEIQKDVFMWRTGDPCPQPMQ 604
            :||..||||:|||...: ||.:::||:||.||..||..:.||             .||     ||
Mosquito  1212 QLRKCDRFWYENEDPVVKFTEQQLAEIRKTTLARIICENLDV-------------GGD-----MQ 1258

  Fly   605 LNATELE--------PCTYLEGYDYFSGSELMFIYVCVFLG--------FVPILCAGAGYCVVKL 653
            ..|.:|.        ||..:...|..:..|.: :..|...|        ..|..|..   |:...
Mosquito  1259 RAAFDLPSNFLNPRVPCNSMPQIDLSAWRENV-VQGCQIGGKNVNVGESAFPSPCTS---CICTN 1319

  Fly   654 QNSKRRRLKIRQEALRAPQHKGSVDKMLAREW 685
            :..:...|:|...|            .|||||
Mosquito  1320 EGPQCASLRITDCA------------QLAREW 1339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duox	NP_608715.2	dual_peroxidase_like	72..625	CDD:188652	179/612 (29%)
		PTZ00184	807..965	CDD:185504
		EFh	860..921	CDD:238008
		PLN02844	<1081..>1393	CDD:215453
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783
LOC1277631	XP_061516638.1	None