Protein Alignment Duox and LOC1270890

DIOPT Version :10

• Sequence 1: NP_608715.2
• Gene: Duox / 33477
• FlyBaseID: FBgn0283531
• Length: 1537
• Species: Drosophila melanogaster
• Sequence 2: XP_309590.6
• Gene: LOC1270890 / 1270890
• VectorBaseID: AGAMI1_007319
• Length: 797
• Species: Anopheles gambiae
• Alignment Length: 618
• Identity: 170/618 - (27%)
• Similarity: 267/618 - (43%)
• Gaps: 143/618 - (23%)

  Fly    70 QRYDGWYNNLAHPD---WGSVDSHLVRKAPPSYSDGVYA-----MAGANRPSTRRLSR------- 119
            :|:||..||: .|.   ||:....:.|..||:|.||::|     ..|...||.|:||.
Mosquito   236 RRFDGRCNNI-EPGGSLWGAAGYPMERLLPPAYGDGIWAPRIVSHTGRYLPSARKLSSTLFADLH 299

  Fly   120 --------LFMRGKDGLGSKFNRTALLAFFGQLVANEI--------------------VMASESG 156
                    |||:                 |||.:|::.                    |..:..|
Mosquito   300 HPHATCNVLFMQ-----------------FGQFLAHDFSRNKPIKTKAKCCTEDGTGRVKDAFPG 347

  Fly   157 C-PIEMHRIEIEKCDEMYDRECRGDKYIPFHRAAY--DRDTGQSPNAPREQINQMTAWIDGSFIY 218
            | |     |.:...|..|.:  .|.:.:.|.|:|.  .||.....:.  .|::.::.:||||.||
Mosquito   348 CMP-----IPVSSGDYFYSQ--HGVRCLHFMRSAVAPTRDCHSVGHG--RQLSAVSHFIDGSAIY 403

  Fly   219 STSEAWLNAMRSFHNGTLLTEKDGKLPVRNTMRVPLFNNPVPSV---MKMLSP--ERLFLLGDPR 278
            .|.....:|:|:...|.|           .::....|:|.:|.:   .....|  |..||.||.|
Mosquito   404 GTDSKQSHALRALEGGRL-----------KSLFHRRFHNELPPLDHTKDACDPAAEMCFLTGDGR 457

  Fly   279 TNQNPAILSFAILFLRWHNTLAQRIKRVHPDWSDEDIYQRARHTVIASLQNVIVYEYLPAFLGTS 343
            :||..::::...||||.||.||:::::::|.|||..::|.||..|||.||::...||||..:|
Mosquito   458 SNQLISLVAVHTLFLREHNRLARQLQKLNPHWSDRTLFQEARRIVIAQLQHIAYGEYLPRVVG-- 520

  Fly   344 LPPY---------------EGYKQDIHPGIGHIFQAAAFRFGHTMIPPGIYRRDGQCNFKETPMG 393
             |.|               |.|....:|.:...|..|||||||:.:|..:..:||..:
Mosquito   521 -PRYMSLYRLHLPVPGTYSEFYSPHTNPSVSSEFTVAAFRFGHSTVPSKLDLQDGPVD------- 577

  Fly   394 YPAVRLCSTW---WDSSGFFADTSVEEVLMGLASQISEREDPVLCSDVRDKL-FGPMEFTRRDLG 454
                    ||   .:.:.|...|..:::|..|..|..:..|.:..:.:...| ..|.:....||.
Mosquito   578 --------TWLTFLNPTRFRERTFYDDLLWSLQRQPMQSVDELFSTSLTRFLNVKPGKQHGVDLA 634

  Fly   455 ALNIMRGRDNGLPDYNTARESYGLKRHKTWTDINPPLFETQPELLDMLKEAYDNKLDDVDVYVGG 519
            |:||.||||:.:..||..|...|.....::.|..       ||:...|:..|.:. ||||:||||
Mosquito   635 AINIQRGRDHAVRPYNDYRRLSGRAGAYSFDDFG-------PEVGSKLRALYPHP-DDVDLYVGG 691

  Fly   520 MLE---SYGQPGEFFTAVIKEQFQRLRDADRFWFEN--ERN-GIFTPEEIAELRKITLWDII-VN 577
            :||   ..|..||.|..:|..||.:.:..||:::.|  :.| |.||..::.|::::||..:| .|
Mosquito   692 ILEPPVDGGVVGETFAELIANQFAKFQRGDRYFYSNGPDTNPGHFTVPQLKEIQRVTLASLICAN 756

  Fly   578 STDVKEEEIQKDVFMWRTGDPCPQPMQLNATEL 610
            :.|..:..:..|.|.....|  .:|:...|.|:
Mosquito   757 AGDPHQMHVVPDAFALPHED--NRPIDCTAPEI 787

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Duox	NP_608715.2	dual_peroxidase_like	72..625	CDD:188652	169/616 (27%)
		PTZ00184	807..965	CDD:185504
		EFh	860..921	CDD:238008
		PLN02844	<1081..>1393	CDD:215453
		NOX_Duox_like_FAD_NADP	1265..1536	CDD:99783
LOC1270890	XP_309590.6	None