DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment G6P and g6pc3

DIOPT Version :9

Sequence 1:	NP_001097063.1	Gene:	G6P / 33476	FlyBaseID:	FBgn0031463	Length:	350	Species:	Drosophila melanogaster
Sequence 2:	NP_001073535.1	Gene:	g6pc3 / 790919	ZFINID:	ZDB-GENE-061215-19	Length:	339	Species:	Danio rerio

Alignment Length:	361	Identity:	89/361 - (24%)
Similarity:	135/361 - (37%)	Gaps:	89/361 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 WAQERLSFG----RPLWHFLSVHLEPNKMFNIIIPLCGIFSQEILVHLFTAFTLISTLNSFEKWI 85
            |..|.|...    ..||...|...:|.....::.|:.....:...:.:.....|...||...|||
Zfish    10 WMAEALQQNSRSLEDLWLVASHMGDPKAAVLLVFPVVFYIHRRTGIAVLWVAALSEWLNLVFKWI 74

  Fly    86 YPETRPLWFLREQFANNVVVKKPAVALESHQLSCEMTGGLPCAHSM----TFTVFVLILASFFFV 146
            ....||.|::.:   :.:..:||. .::..|.:||...|.|..|:|    .:.|.:..||||
Zfish    75 LFGERPYWWIGQ---SGLFSEKPP-EVQQFQSTCESGPGSPSGHAMVTSAVWWVIISSLASF--- 132

  Fly   147 HCWDRFAALRSSFCRCIMYLLIIGMVVCMWLSRLYLATEFLHQCILGSYLGI-------RSLCTF 204
                ..|...|.....::|||....:.|:.|||:::...|.||.:.|...|:       ||:
Zfish   133 ----SQAYTGSKILSAVLYLLYAVFLGCVGLSRIFILAHFPHQVVAGLLTGVLLGVFLKRSV--- 190

  Fly   205 EGNVKYLFSRPRRYAVSAVFF------LGGLALSVYYVKLELNIDPHWSVREAFKWCPEPTYLRH 263
                      |.|..:  :||      |.|.||..:.|..:..||..||:..|.:||....::|.
Zfish   191 ----------PERRPL--LFFFRFSMALLGAALIFHAVLEKTGIDLSWSISLAKRWCSRSEWVRM 243

  Fly   264 EVGPIFALVRDLGNLMGLALASPLYKLEMKQSSFWR------------RCRFLGVLEFVNYGLRF 316
            :..|..:|.||.|.|:||.||           .:|:            .|..|..|. ::|..||
Zfish   244 DTAPFSSLNRDAGVLLGLGLA-----------QYWKPGGWTLPRAPRTLCLALSSLA-LHYISRF 296

  Fly   317 -----------STFKQSGRFVFLTYEFLRNVIHSLV 341
                       |.|       ||.|..:..|:..||
Zfish   297 PLPTVPPLLFYSLF-------FLKYSIVPQVVMVLV 325

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
G6P	NP_001097063.1	PAP2_glucose_6_phosphatase	49..290	CDD:239476	67/257 (26%)
g6pc3	NP_001073535.1	PgpB	<39..200	CDD:223743	43/186 (23%)
g6pc3	NP_001073535.1	PAP2_like	40..269	CDD:294324	68/265 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580229
Domainoid	1	1.000	57	1.000	Domainoid score	I10819
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I5001
OMA	1	1.010	-	-		QHG49592
OrthoDB	1	1.010	-	-		D325559at33208
OrthoFinder	1	1.000	-	-		FOG0001425
OrthoInspector	1	1.000	-	-		otm25162
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR12591
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5586
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	11.000