Protein Alignment CG2964 and pykA

DIOPT Version :10

• Sequence 1: NP_608713.2
• Gene: CG2964 / 33475
• FlyBaseID: FBgn0031462
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: NP_416368.1
• Gene: pykA / 946527
• ECOCYCID: EG10803
• Length: 480
• Species: Escherichia coli
• Alignment Length: 495
• Identity: 160/495 - (32%)
• Similarity: 255/495 - (51%)
• Gaps: 36/495 - (7%)

  Fly    32 RLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALERIHKETGQIRT 96
            |...::.|:..::...:.:..:|..|.|:.|:||||.|.|.|....:.:.|...::.      |.
E. coli     6 RRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVREIAAKLG------RH 64

  Fly    97 VAIAADTRGPQIRTGLL-DGDVFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLF 160
            |||..|.:||:||.... :|.|||..||...|..|.. ..:|:||.|.:||..:......||.|.
E. coli    65 VAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLG-KGEGDKEKVGIDYKGLPADVVPGDILL 128

  Fly   161 IDDGRLLLHILEVGVDGLLCEVIHGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQFSIKANVDFL 225
            :||||:.|.:|||....:..||..||.|:||..:......:...|::|||..||:.:....||:|
E. coli   129 LDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNKGINKLGGGLSAEALTEKDKADIKTAALIGVDYL 193

  Fly   226 FASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIAL---SRFSEILRAADGLLLSRADLGTQIP 287
            ..|..|..:::...|.:..:.|...||:||::...|:   ....:|:.|:|.::::|.|||.:|.
E. coli   194 AVSFPRCGEDLNYARRLARDAGCDAKIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIG 258

  Fly   288 IEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAI 352
            ..:|...||:::.:..::.:.||.|:.::|||.|.|.|||||..|:|||::||.|.:|||:|.|.
E. coli   259 DPELVGIQKALIRRARQLNRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAA 323

  Fly   353 GSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGEL---DAAHSLAIAAVETAKR-TNATLI 413
            |.:|.||||....:|..|||:.      |..||:.|.::   :...::|::|:..|.. ...|.|
E. coli   324 GQYPSETVAAMARVCLGAEKIP------SINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAI 382

  Fly   414 IVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPSTDYATDVDARVQFA 478
            |.:|.|||:|.:.|:.....||.|::|.|||.....|:|||.|:.:      |.|.|..|....|
E. coli   383 ITMTESGRTALMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHF------DSANDGVAAASEA 441

  Fly   479 MTSAKKWGIIDDGDPIVIVSAWKDGG-----GFTNNVRVV 513
            :...:..|.:..||.:::.    .|.     |.||..|::
E. coli   442 VNLLRDKGYLMSGDLVIVT----QGDVMSTVGSTNTTRIL 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:453956	160/495 (32%)
pykA	NP_416368.1	PRK05826	3..469	CDD:235619	156/485 (32%)