DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2964 and AT5G56350

DIOPT Version :9

Sequence 1:	NP_608713.2	Gene:	CG2964 / 33475	FlyBaseID:	FBgn0031462	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_200446.1	Gene:	AT5G56350 / 835735	AraportID:	AT5G56350	Length:	498	Species:	Arabidopsis thaliana

Alignment Length:	480	Identity:	166/480 - (34%)
Similarity:	271/480 - (56%)	Gaps:	30/480 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 LIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALERIHKETGQIRTVAIA 100
            ::.|:..:||:...:..::..|:|:.|.||||.|||.|.:|::.:::|:    ..||.:  .|:.
plant    12 IVCTLGPASRSVPMVEKLLRAGMNVARFNFSHGSHEYHQETLDNLHQAM----LNTGIL--CAVM 70

  Fly   101 ADTRGPQIRTGLL-DG-DVFLRSGDNLRLSINRDLYDKGNKEAVYVDYPNIINLTKTGDRLFIDD 163
            .||:||:||||.| || .:.|:.|..:.:|.:.||  ||::..:.:.|..:......|..:...|
plant    71 LDTKGPEIRTGFLKDGKPIQLKQGQEITISTDYDL--KGDENTICMSYKKLAVDVNPGMVILCAD 133

  Fly   164 GRLLLHIL----EVGVDGLLCEVIHGGQLNNNCNVILPEIEIDLPAVSEKDMFDI-QFSIKANVD 223
            |.:.|.:|    |.|.....||  :...|....||.||.:.:|||.::|||..|| |:.:...:|
plant   134 GTISLLVLSCDKENGTVRCRCE--NSAMLGERKNVNLPGVVVDLPTLTEKDKEDIMQWGVPNQID 196

  Fly   224 FLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPI 288
            .:..|.||...::.::|.:||:..|:|.:::|::::..::.|.:||..:|..:::|.|||.:|||
plant   197 MIALSFVRKGSDLVQVRKLLGKHAKNILLMSKVENQEGVANFDDILVNSDAFMIARGDLGMEIPI 261

  Fly   289 EKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIG 353
            ||:|:.||.::.:||..||||:.|:.:||||...|.|||||..|:|||::||.||:|||.|.|.|
plant   262 EKIFLAQKVMIYKCNIQGKPVVTATQMLESMIKSPRPTRAEATDVANAVLDGTDCVMLSGETAAG 326

  Fly   354 SFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAIAAVETAKRTNATLIIVLTT 418
            ::|:..|.|...:|.|||..|.:.|:|..::......:....|||.:||.||....||||:|||.
plant   327 AYPELAVRTMAKICVEAESTLDYGDVFKRIMLYSPVPMSPLESLASSAVRTANSARATLIMVLTR 391

  Fly   419 SGRSATLVSKFRPRCPIMAIT-----------RC--ERTARWVYLHRGVLPILYTLEPSTDYATD 470
            .|.:|.||:|:||..||:::.           .|  |..||...:.||::|:||.......:...
plant   392 GGSTARLVAKYRPGMPILSVVVPEIKTDFFDWSCSDESPARHSLIFRGLIPVLYAGSARASHDES 456

  Fly   471 VDARVQFAMTSAKKWGIIDDGDPIV 495
            .:..::||....|:..:...||.:|
plant   457 TEEAIEFATQYGKEKELCKTGDSVV 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:304951	166/480 (35%)
CG2964	NP_608713.2	pyruv_kin	32..512	CDD:273424	166/480 (35%)
AT5G56350	NP_200446.1	PLN02461	2..498	CDD:215255	166/480 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3652
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	410	1.000	Inparanoid score	I455
OMA	1	1.010	-	-		QHG53565
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	1	1.000	-	-		FOG0000841
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.840