DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2964 and AT3G55650

DIOPT Version :9

Sequence 1:	NP_608713.2	Gene:	CG2964 / 33475	FlyBaseID:	FBgn0031462	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_191124.1	Gene:	AT3G55650 / 824731	AraportID:	AT3G55650	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	500	Identity:	172/500 - (34%)
Similarity:	274/500 - (54%)	Gaps:	33/500 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 ELDLAQQASHQRLVS---LIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINE 82
            |:.|..||::..|.|   :|.|:...||:.:.|..::..|:|:.|.||||.||..|.:|::.:..
plant     2 EMLLGGQATNGALRSKTKIICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRT 66

  Fly    83 ALERIHKETGQIRTVAIAADTRGPQIRTGLL-DG-DVFLRSGDNLRLSINRDLYDKGNKEAVYVD 145
            |::    .||.:.  |:..||:||:||||.| :| .:.|..|..:.:||  |...:|:...:.:.
plant    67 AMD----NTGILS--AVMLDTKGPEIRTGFLKEGKPIQLNQGQEITISI--DYMIEGDSNVISMS 123

  Fly   146 YPNIINLTKTGDRLFIDDGRLLLHILEVGVD-GLL-CEVIHGGQLNNNCNVILPEIEIDLPAVSE 208
            |..:....|.||.:...||.:.|.:|..... ||: |...:...|....||.||.|.:|||.::|
plant   124 YKKLAEDVKPGDVILCSDGTISLTVLSCDKSFGLVRCRCENSAILGERKNVNLPGIVVDLPTLTE 188

  Fly   209 KDMFD-IQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEILRAA 272
            ||..| ||:.:...:|.:..|.||...::.|:|.:|||..|:|.:::|::::..:....:||..:
plant   189 KDKEDIIQWGVPNKIDIIALSFVRKGSDLTEVRRLLGEHSKNIMLMSKVENQEGVMNCEKILENS 253

  Fly   273 DGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLANAI 337
            |..:::|.|||.:|||||:|:.||:::...|.:||||:.|:.:||||...|.|||||..|:|||:
plant   254 DAFMVARGDLGMEIPIEKMFLAQKTMIKMANALGKPVVTATQMLESMTVSPRPTRAEATDVANAV 318

  Fly   338 IDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAIAAV 402
            :||.||:|||.|.|.|:.|:..|.|...:|:|||..:.:..|....:..|...|....|||.:.|
plant   319 LDGTDCVMLSGETAAGAHPEAAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASVV 383

  Fly   403 ETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCE----------------RTARWVYLH 451
            .||:...|:.|:|||..|.:|.||:|:||..||:::...|                ..||...::
plant   384 STAQSVFASAIVVLTKGGYTAELVAKYRPSVPILSVIVPEIAQGNDMEMSCSDSVAHAARRGLIY 448

  Fly   452 RGVLPILYTLEPSTDYATD-VDARVQFAMTSAKKWGIIDDGDPIV 495
            |.::|::.|...:.|...| .:..:..|:..||..||..:||.||
plant   449 RRIIPVVATGSSARDSNKDATEEMINLAIGFAKTKGICKNGDSIV 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:304951	167/488 (34%)
CG2964	NP_608713.2	pyruv_kin	32..512	CDD:273424	167/488 (34%)
AT3G55650	NP_191124.1	PLN02461	1..510	CDD:215255	171/499 (34%)
AT3G55650	NP_191124.1	Pyruvate_Kinase	17..509	CDD:304951	165/484 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3652
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	410	1.000	Inparanoid score	I455
OMA	1	1.010	-	-		QHG53565
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.840