DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2964 and AT3G52990

DIOPT Version :9

Sequence 1:	NP_608713.2	Gene:	CG2964 / 33475	FlyBaseID:	FBgn0031462	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_566976.1	Gene:	AT3G52990 / 824465	AraportID:	AT3G52990	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	531	Identity:	151/531 - (28%)
Similarity:	278/531 - (52%)	Gaps:	58/531 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LSAKSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSH 67
            :.:..:|.|...:::.|  |:.::.:....|..::.|:...||:.:.:...:..|:::.|.:||.
plant     1 MHSSHLLLEEPIRMASI--LEPSKSSFFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSW 63

  Fly    68 ESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRT-GLLDGDVFLRSGDNLRLSINR 131
            ...:.|.:|::.:..|:....|      ..|:..||.||:::. ...:..:.|::...:.|:.|:
plant    64 GDADYHQETLDNLKVAVRSTKK------LCAVMLDTVGPELQVINKSEKAITLKADGLVTLTPNQ 122

  Fly   132 DLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLL----------LHILEVGVDGLLCEVIHGG 186
            |  .:.:.|.:.:::..:....|.||.:|:  |:.|          |.:.||..|.::|
plant   123 D--QEASSEVLPINFNGLAKAVKKGDTIFV--GQYLFTGSETTSVWLEVDEVKGDDVIC------ 177

  Fly   187 QLNNNCNVIL--------PEIEIDLPAVSEKDMFDIQ-FSIKANVDFLFASAVRSAKNVKELRTV 242
             |:.|...:.        .::.||||.::|||...|. :.::..:|||..|..|.|::|::.|.:
plant   178 -LSRNAATLAGSLFTLHSSQVHIDLPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQTREM 241

  Fly   243 LGEKG--KHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKV 305
            |.:.|  ...:|.||:::...|:.|.|||:.|||::|||.:||..:|.||:|:.||:.|.:||..
plant   242 LKKLGDLSQTQIFAKIENVEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMA 306

  Fly   306 GKPVIVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREA 370
            |||.:: :.:::||.....|||||..|:|||::||:|.|:|.:|...|.:|.||::|...:|.||
plant   307 GKPAVL-TRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICAEA 370

  Fly   371 EKVLWFRDL-FSDLVSEVRGELDAAHSLAIAAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCP 434
            ||| :.:|| |...|..|...:....|:|.:||..|.:..|::||..|:|||:|.|::|:||..|
plant   371 EKV-FNQDLYFKKTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMP 434

  Fly   435 IMA--ITRCERT-----------ARWVYLHRGVLPILY-TLEPSTDYATDVDARVQFAMTSAKKW 485
            :::  |.|.:..           ||...:.||:.|:|. ...|:...:...::.::.|:...|..
plant   435 VISVVIPRVKTNQLKWSFSGAFEARQSLIVRGLFPMLADPRHPAESTSATNESVLKVALDHGKHA 499

  Fly   486 GIIDDGDPIVI 496
            |:|...|.:|:
plant   500 GVIKSHDRVVV 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:304951	147/502 (29%)
CG2964	NP_608713.2	pyruv_kin	32..512	CDD:273424	147/502 (29%)
AT3G52990	NP_566976.1	PLN02765	1..527	CDD:215409	151/531 (28%)
AT3G52990	NP_566976.1	Pyruvate_Kinase	30..523	CDD:304951	146/500 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3652
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880