DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2964 and AT3G04050

DIOPT Version :9

Sequence 1:	NP_608713.2	Gene:	CG2964 / 33475	FlyBaseID:	FBgn0031462	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_187055.1	Gene:	AT3G04050 / 819560	AraportID:	AT3G04050	Length:	510	Species:	Arabidopsis thaliana

Alignment Length:	512	Identity:	174/512 - (33%)
Similarity:	275/512 - (53%)	Gaps:	63/512 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 LAQQASHQRLVS---LIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALE 85
            ||.|.::..|.|   ::.|:..:||:.:.:..::..|:|:.|.||||.||..|.:|::.:..|:|
plant     5 LAGQTNNGSLKSKTKIVCTLGPASRSVEMVEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAME 69

  Fly    86 RIHKETGQIRTVAIAADTRGPQIRTGLLDGDVFLRSGDNLRL------SINRDLYDKGNKEAVYV 144
                  ......|:..||:||:||||      ||:.|..:.|      :|:.|...:|:...:.:
plant    70 ------NTCIPCAVMLDTKGPEIRTG------FLKEGKPVELIQGQEITISTDYTMEGDSNTISM 122

  Fly   145 DYPNIINLTKTGDRLFIDDGRLLLHIL----EVGVDGLLCEVIHGGQLNNNCNVILPEIEIDLPA 205
            .|..:....|:||.:...||.:.|.:|    .:|:....||  :...|....||.||.|.:|||.
plant   123 SYKKLAEDLKSGDVILCSDGTISLTVLSCDKNLGLVRARCE--NSAVLGERKNVNLPGIVVDLPT 185

  Fly   206 VSEKDMFDI-QFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEIL 269
            ::|||..|| |:.:...:|.:..|.||...::.|:|.:|||..|.|.:::|::::..:..|.:||
plant   186 LTEKDQEDILQWGVPNKIDIIALSFVRKGSDLVEVRKLLGENAKSIMLMSKVENQEGVMNFDKIL 250

  Fly   270 RAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLA 334
            ..:|..:::|.|||.:|||||:|:.||.::.:.|.:|||::.|:.:||||...|.|||||..|:|
plant   251 EYSDAFMVARGDLGMEIPIEKMFLAQKMMIQKANALGKPIVTATQMLESMTKSPRPTRAEATDVA 315

  Fly   335 NAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAI 399
            ||::||.||:|||.|.|.|:.|:..|.|...:|:|||..:.:..:...:...|...|....|||.
plant   316 NAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDTMHKKIQDIVSLPLSPIESLAA 380

  Fly   400 AAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMA-----ITR-------CERTARWV---- 448
            :||.||:...|..|:|||..|.:..||:|:||..||::     |||       |..:|..|
plant   381 SAVSTARSLCAAAIVVLTKGGYTVELVAKYRPSVPILSVIVPEITRTDDFEWSCSESAAHVARRG 445

  Fly   449 YLHRGVLPILYTLEPSTDYATDVDAR----------VQFAMTSAKKWGIIDDGDPIV 495
            .::||::|::         ||...||          :|||:..|||.||...||.||
plant   446 LIYRGIVPVM---------ATGASARSSNKDSTEETIQFAIEFAKKKGICKTGDSIV 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:304951	171/504 (34%)
CG2964	NP_608713.2	pyruv_kin	32..512	CDD:273424	171/504 (34%)
AT3G04050	NP_187055.1	PLN02461	1..510	CDD:215255	174/512 (34%)
AT3G04050	NP_187055.1	Pyruvate_Kinase	17..496	CDD:304951	169/500 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3652
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	410	1.000	Inparanoid score	I455
OMA	1	1.010	-	-		QHG53565
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.840