DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2964 and AT2G36580

DIOPT Version :9

Sequence 1:	NP_608713.2	Gene:	CG2964 / 33475	FlyBaseID:	FBgn0031462	Length:	554	Species:	Drosophila melanogaster
Sequence 2:	NP_565850.1	Gene:	AT2G36580 / 818231	AraportID:	AT2G36580	Length:	527	Species:	Arabidopsis thaliana

Alignment Length:	527	Identity:	150/527 - (28%)
Similarity:	282/527 - (53%)	Gaps:	50/527 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LSAKSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSH 67
            :.:..:|.|...:::.|  |:.::.:....|..::.|:...||:.:.|...:..|:::.|.:||.
plant     1 MHSSHLLLEEPIRMTSI--LEPSKSSFFPALTKIVGTLGPKSRSVEVIAGCLKAGMSVARFDFSW 63

  Fly    68 ESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRT-GLLDGDVFLRSGDNLRLSINR 131
            ...:.|.:|:|.:..|::...|      ..|:..||.||:::. ...:..:.|::...:.|:.::
plant    64 CDADYHQETLENLKIAVKSTKK------LCAVMLDTVGPELQVINKTEKAISLKADGLVTLTPSQ 122

  Fly   132 DLYDKGNKEAVYVDYPNIINLTKTGDRLFIDDGRLL----------LHILEVGVDGLLC----EV 182
            |  .:.:.|.:.:::..:....|.||.:|:  |:.|          |.:.||..|.::|    ..
plant   123 D--QEASSEVLPINFDGLAKAVKKGDTIFV--GQYLFTGSETTSVWLEVEEVKGDDVICISRNAA 183

  Fly   183 IHGGQLNNNCNVILPEIEIDLPAVSEKDMFDIQ-FSIKANVDFLFASAVRSAKNVKELRTVLGEK 246
            ..||.|   ..:.:.::.||:|.::|||...|. :.::..:|||..|..|.|::|::.|.:|...
plant   184 TLGGPL---FTLHVSQVHIDMPTLTEKDKEVISTWGVQNKIDFLSLSYCRHAEDVRQARELLNSC 245

  Fly   247 G--KHIKIIAKMDSKIALSRFSEILRAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPV 309
            |  ...:|.||::::..|:.|.|||:.|||::|||.:||..:|.||:|:.||:.|.:||..|||.
plant   246 GDLSQTQIFAKIENEEGLTHFDEILQEADGIILSRGNLGIDLPPEKVFLFQKAALYKCNMAGKPA 310

  Fly   310 IVASHILESMRTLPHPTRAECFDLANAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVL 374
            :: :.:::||.....|||||..|:|||::||:|.|:|.:|...|.:|.||::|...:|.|||||
plant   311 VL-TRVVDSMTDNLRPTRAEATDVANAVLDGSDAILLGAETLRGLYPVETISTVGRICCEAEKV- 373

  Fly   375 WFRDLFSDLVSEVRGE-LDAAHSLAIAAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAI 438
            :.:|||.....:..|| :....|:|.:||..|.:..|::||..|:|||:|.|::|:||..|::::
plant   374 FNQDLFFKKTVKYVGEPMTHLESIASSAVRAAIKVKASVIICFTSSGRAARLIAKYRPTMPVLSV 438

  Fly   439 TRCERTA---RWVY----------LHRGVLPILY-TLEPSTDYATDVDARVQFAMTSAKKWGIID 489
            .....|.   :|.:          :.||:.|:|. ...|:...:...::.::.|:...|:.|:|.
plant   439 VIPRLTTNQLKWSFSGAFEARQSLIVRGLFPMLADPRHPAESTSATNESVLKVALDHGKQAGVIK 503

  Fly   490 DGDPIVI 496
            ..|.:|:
plant   504 SHDRVVV 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:304951	146/498 (29%)
CG2964	NP_608713.2	pyruv_kin	32..512	CDD:273424	146/498 (29%)
AT2G36580	NP_565850.1	PLN02765	1..527	CDD:215409	150/527 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	64	1.000	Domainoid score	I3652
eggNOG	1	0.900	-	-		E1_COG0469
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D933620at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	6	5.880