Protein Alignment CG2964 and pkm

DIOPT Version :10

• Sequence 1: NP_608713.2
• Gene: CG2964 / 33475
• FlyBaseID: FBgn0031462
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: NP_001016470.1
• Gene: pkm / 549224
• XenbaseID: XB-GENE-485873
• Length: 527
• Species: Xenopus tropicalis
• Alignment Length: 506
• Identity: 230/506 - (45%)
• Similarity: 330/506 - (65%)
• Gaps: 8/506 - (1%)

  Fly    14 TQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIE 78
            |.|.|:|.||:..:....|...:|.||..:||:.:.:..||..|:||.||||||.:||.|:.||:
 Frog    21 TFLEHMCRLDIDSEPIVARNTGIICTIGPASRSVEILKEMIKSGMNIARLNFSHGTHEYHAGTIK 85

  Fly    79 LINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRSGDNLRLSINRDLYDKGNK 139
            .:.||.|.........|.||:|.||:||:|||||:.|    :|.|:.|..||::::....:|.::
 Frog    86 NVREATESFSSNPIHYRPVAVALDTKGPEIRTGLIKGSGTAEVELKKGATLRITLDDAFQEKCDE 150

  Fly   140 EAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCEVIHGGQLNNNCNVILPEIEIDLP 204
            ..::|||.|:..:.|.|.::::|||.:.|.:.|.|.|..|.||.:||.|.:...|.||...:|||
 Frog   151 NILWVDYKNLTKVVKPGSKIYVDDGLISLLVKETGADFCLTEVENGGMLGSKKGVNLPGAAVDLP 215

  Fly   205 AVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEIL 269
            |||.||:.|:||.::.|||.:|||.:|.|.:|..:|.|||||||:||||:|:::...:.||.|||
 Frog   216 AVSTKDIQDLQFGVEQNVDMVFASFIRKAADVHAVRKVLGEKGKNIKIISKIENHEGVRRFDEIL 280

  Fly   270 RAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLA 334
            .|:||::::|.|||.:||.||:|:.||.::|:||:.|||||.|:.:||||...|.|||||..|:|
 Frog   281 EASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVA 345

  Fly   335 NAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDL--VSEVRGELDAAHSL 397
            ||::|||||||||.|.|.|.:|.|.|.....:.||||..::.|.||.:|  ||.:  ..|...:.
 Frog   346 NAVLDGADCIMLSGETAKGDYPLEAVRMQHAIAREAEAAIFHRQLFEELRRVSPL--TRDPTEAT 408

  Fly   398 AIAAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLE 462
            |:.|||::.:.::..|||||.|||||.|||::|||.||:|:||..:|||..:|:||:.|:||...
 Frog   409 AVGAVESSFKCSSGAIIVLTKSGRSAHLVSRYRPRAPIIAVTRNGQTARQAHLYRGIFPVLYREA 473

  Fly   463 PSTDYATDVDARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVV 513
            ....:|.|||.||.|||...|..|....||.:::::.|:.|.||||.:|||
 Frog   474 VHEAWAEDVDMRVNFAMDIGKARGFFKSGDVVIVLTGWRPGSGFTNTMRVV 524

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:453956	224/488 (46%)
pkm	NP_001016470.1	Pyruvate_Kinase	38..526	CDD:238178	224/489 (46%)