Protein Alignment CG2964 and pyk1

DIOPT Version :10

• Sequence 1: NP_608713.2
• Gene: CG2964 / 33475
• FlyBaseID: FBgn0031462
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: NP_594346.1
• Gene: pyk1 / 2543557
• PomBaseID: SPAC4H3.10C
• Length: 509
• Species: Schizosaccharomyces pombe
• Alignment Length: 499
• Identity: 196/499 - (39%)
• Similarity: 301/499 - (60%)
• Gaps: 12/499 - (2%)

  Fly    21 ELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIELINEALE 85
            |||:   .:..|..|:|.||...|.|.:|:..:...|:||.|:||||.|:|.|...|:...:|
pombe    18 ELDI---PAVNRRTSIICTIGPKSNNVETLCKLRDAGMNIVRMNFSHGSYEYHQSVIDNARKA-- 77

  Fly    86 RIHKETGQIRTVAIAADTRGPQIRTGLLDG--DVFLRSGDNLRLSINRDLYDKGNKEAVYVDYPN 148
               ..|..:..:|||.||:||:|||||..|  |..:.||..:..:.:....:|.|.:.:|:||.|
pombe    78 ---SATNPLFPLAIALDTKGPEIRTGLTVGGTDYPISSGHEMIFTTDDAYAEKCNDKVMYIDYKN 139

  Fly   149 IINLTKTGDRLFIDDGRLLLHILE-VGVDGLLCEVIHGGQLNNNCNVILPEIEIDLPAVSEKDMF 212
            |..:.:.|..:::|||.|...::| |....|...|.:.|::::...|.||:.::||||:||||..
pombe   140 ITKVIQPGRIIYVDDGILSFTVIEKVDDKNLKVRVNNNGKISSKKGVNLPKTDVDLPALSEKDKA 204

  Fly   213 DIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEILRAADGLLL 277
            |::|.:|..||.:|||.:|.|::|..:|.||||:||:||||.|::::..::.|..||...||:::
pombe   205 DLRFGVKNGVDMIFASFIRRAEDVIHIREVLGEEGKNIKIICKIENQQGVNNFDSILDVTDGIMV 269

  Fly   278 SRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLANAIIDGAD 342
            :|.|||.:||..::|:.||.::.:||..||||..|:.:||||...|.|||||..|:.||::||||
pombe   270 ARGDLGIEIPASQVFVAQKMMIAKCNIAGKPVACATQMLESMTYNPRPTRAEVSDVGNAVLDGAD 334

  Fly   343 CIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELD-AAHSLAIAAVETAK 406
            .:|||.|...||:|.|.|.......|.||..:.:..|:.::...||..|: |..:.|:||:..:.
pombe   335 LVMLSGETTKGSYPVEAVTYMAETARVAEASIPYGSLYQEMFGLVRRPLECATETTAVAAIGASI 399

  Fly   407 RTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPSTDYATDV 471
            .::|..|:||:|||.:|.|.||:||..||:.:|||.:.||..:|:|||.|::|..||.:|:..||
pombe   400 ESDAKAIVVLSTSGNTARLCSKYRPSIPIVMVTRCPQRARQSHLNRGVYPVIYEKEPLSDWQKDV 464

  Fly   472 DARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVVYA 515
            ||||.:....|.|..|:..||.|:::.....|.|.|:..|:..|
pombe   465 DARVAYGCQQAYKMNILKKGDKIIVLQGAVGGKGHTSIFRLTVA 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:453956	192/486 (40%)
pyk1	NP_594346.1	Pyruvate_Kinase	25..508	CDD:238178	192/487 (39%)