Protein Alignment CG2964 and Pklr

DIOPT Version :10

• Sequence 1: NP_608713.2
• Gene: CG2964 / 33475
• FlyBaseID: FBgn0031462
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: XP_006232655.1
• Gene: Pklr / 24651
• RGDID: 3336
• Length: 574
• Species: Rattus norvegicus
• Alignment Length: 504
• Identity: 227/504 - (45%)
• Similarity: 325/504 - (64%)
• Gaps: 4/504 - (0%)

  Fly    14 TQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIE 78
            |.|.|:|.||:..|....|..|:||||..:||:.|.:..||..|:||.||||||.|||.|:::|.
  Rat    68 TFLEHLCLLDIDSQPVAARSTSIIATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIA 132

  Fly    79 LINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRSGDNLRLSINRDLYDKGNK 139
            .|.||.|.........|.||||.||:||:||||:|.|    :|.:..|..:.::::.....:|:.
  Rat   133 NIREATESFATSPLSYRPVAIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFQTRGDA 197

  Fly   140 EAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCEVIHGGQLNNNCNVILPEIEIDLP 204
            :.|:|||.||..:...|.|::||||.:.|.:.::|.:||:.||.|||.|.:...|.||..|:|||
  Rat   198 KTVWVDYHNITRVVAVGGRIYIDDGLISLVVQKIGPEGLVTEVEHGGILGSRKGVNLPNTEVDLP 262

  Fly   205 AVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEIL 269
            .:||:|:.|::|.::.|||.:|||.||.|.:|..:|..||.:|::||||:|:::...:.:|.|||
  Rat   263 GLSEQDLLDLRFGVQHNVDIIFASFVRKASDVLAVRDALGPEGQNIKIISKIENHEGVKKFDEIL 327

  Fly   270 RAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLA 334
            ..:||::::|.|||.:||.||:|:.||.::|:||..||||:.|:.:||||.|...|||||..|:|
  Rat   328 EVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDVA 392

  Fly   335 NAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAI 399
            ||::|||||||||.|.|.||||.|.|.....:.||||..::.|.||.:|........|.....||
  Rat   393 NAVLDGADCIMLSGETAKGSFPVEAVMMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAI 457

  Fly   400 AAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPS 464
            .|||.:.:..|..|||||.:||||.|:|::|||..::|:||..:.||.|:|.|||.|:||...|.
  Rat   458 GAVEASFKCCAAAIIVLTKTGRSAQLLSQYRPRAAVIAVTRSAQAARQVHLSRGVFPLLYREPPE 522

  Fly   465 TDYATDVDARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVV 513
            ..:|.|||.||||.:.|.|..|.:..||.:::|:.|:.|.|:||.:||:
  Rat   523 AIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVL 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:453956	220/486 (45%)
Pklr	XP_006232655.1	Pyruvate_Kinase	85..573	CDD:238178	220/487 (45%)