Protein Alignment CG2964 and pyk-1

DIOPT Version :9

• Sequence 1: NP_608713.2
• Gene: CG2964 / 33475
• FlyBaseID: FBgn0031462
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: NP_001379495.1
• Gene: pyk-1 / 172744
• WormBaseID: WBGene00009126
• Length: 913
• Species: Caenorhabditis elegans
• Alignment Length: 507
• Identity: 208/507 - (41%)
• Similarity: 321/507 - (63%)
• Gaps: 8/507 - (1%)

  Fly    13 STQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTI 77
            :|.:.|:|.||:.:.....|...:|.||..:..:.:.:..:|:.|:||.||||||.|||.|:.||
 Worm   410 TTHMEHLCRLDIREAPHLVRQTGIICTIGPACASVEMLQKLILNGMNIARLNFSHGSHEYHAGTI 474

  Fly    78 ELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRSGDNLRLSINRDLYDKGN 138
            ..:.||.:....:    |.:.||.||:||:||||||.|    ::.|..|.::||:.:....:.|.
 Worm   475 ANVREAADSFSDK----RVIGIALDTKGPEIRTGLLAGGASAEIELARGASIRLTTDPHFSESGT 535

  Fly   139 KEAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCEVIHGGQLNNNCNVILPEIEIDL 203
            ...::|||.||..:...|.|::||||.:.|.:.|:..|.::|.|.:||.|.:...|.||...:||
 Worm   536 AVNLFVDYKNIAKVLSVGSRVYIDDGLISLIVEELQTDAVICSVENGGMLGSRKGVNLPGTIVDL 600

  Fly   204 PAVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEI 268
            |||||||..|:||.::..||.:|||.:|:|:.::.:|.|||||||.||||||::::..:....||
 Worm   601 PAVSEKDCKDLQFGVEQGVDIIFASFIRNAEGIRTIRKVLGEKGKKIKIIAKIENQEGVDNADEI 665

  Fly   269 LRAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDL 333
            :..:||::::|.|||.:||.||:|:.||.::.:||:.|||||.|:.:||||...|.|||||..|:
 Worm   666 ISESDGVMVARGDLGIEIPAEKVFLAQKMLISKCNRAGKPVICATQMLESMVHKPRPTRAEGSDV 730

  Fly   334 ANAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLA 398
            |||::|||||:|||.|.|.|.:|.:.:.....:|:|||..::.|.||.:|:...:...|.:|::|
 Worm   731 ANAVLDGADCVMLSGETAKGEYPVDALKIMHYICKEAEAAVYHRRLFDELLQNTQKPTDMSHTIA 795

  Fly   399 IAAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEP 463
            |||...|...:|:.|:::||:||||...|:::|..||:.|:|.....|.::|:|||.|:.|..|.
 Worm   796 IAATSAAASCHASAILLITTTGRSAIQCSRYKPAVPILTISRDVAVCRQLHLYRGVFPVHYPAER 860

  Fly   464 STDYATDVDARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVVYA 515
            :.|:.||||.|:..|:...|..|.|..||.:|:|:.|:.|.|.||.:|::.|
 Worm   861 AADWPTDVDNRINHAIAIGKDRGFIHKGDFLVVVTGWRQGAGATNTLRIITA 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:304951	202/486 (42%)
		pyruv_kin	32..512	CDD:273424	201/483 (42%)
pyk-1	NP_001379495.1	Pyruvate_Kinase	429..912	CDD:238178	202/486 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159193
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S493
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D219692at33208
OrthoFinder	1	1.000	-	-		FOG0000841
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100258
Panther	1	1.100	-	-	O	PTHR11817
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X374
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.800