Protein Alignment CG2964 and pklr

DIOPT Version :10

• Sequence 1: NP_608713.2
• Gene: CG2964 / 33475
• FlyBaseID: FBgn0031462
• Length: 554
• Species: Drosophila melanogaster
• Sequence 2: XP_031747000.1
• Gene: pklr / 100380137
• XenbaseID: XB-GENE-5918041
• Length: 549
• Species: Xenopus tropicalis
• Alignment Length: 504
• Identity: 223/504 - (44%)
• Similarity: 325/504 - (64%)
• Gaps: 4/504 - (0%)

  Fly    14 TQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNFSHESHEMHSKTIE 78
            |.|.|:|.||:..:....|..|::.||..:||:.:.:..||..|:||.||||||.|||.|:.:|:
 Frog    43 TFLEHMCLLDIDSEPITARNTSIVCTIGPASRSVEMLKEMIKAGMNIARLNFSHGSHEYHAGSIQ 107

  Fly    79 LINEALERIHKETGQIRTVAIAADTRGPQIRTGLL----DGDVFLRSGDNLRLSINRDLYDKGNK 139
            .|.:|.|.........|.||||.||:||:||||::    :.:|.|..|..::::.:....||.::
 Frog   108 NIRDATESFASNPTHYRPVAIALDTKGPEIRTGVIKTGENAEVELAKGSVVKVTTDESFKDKCDE 172

  Fly   140 EAVYVDYPNIINLTKTGDRLFIDDGRLLLHILEVGVDGLLCEVIHGGQLNNNCNVILPEIEIDLP 204
            :.::|||.||..:.|.|.|:|:|||.:.|.:.|:|.|..:.||.:||.|.:...|.||..::|||
 Frog   173 QTLWVDYKNISKVVKVGGRIFVDDGLISLLVKEIGPDYCMTEVENGGNLCSKKGVNLPGAQVDLP 237

  Fly   205 AVSEKDMFDIQFSIKANVDFLFASAVRSAKNVKELRTVLGEKGKHIKIIAKMDSKIALSRFSEIL 269
            |:||:|..|:||.|:..||.:|||.:|.|::|..:|..|||||.:|:||:|:::...:.||.|||
 Frog   238 ALSERDCLDLQFGIEQGVDMVFASFIRKAQDVHAIRQKLGEKGGNIRIISKIENHEGVKRFDEIL 302

  Fly   270 RAADGLLLSRADLGTQIPIEKLFITQKSILGQCNKVGKPVIVASHILESMRTLPHPTRAECFDLA 334
            .|:||::::|.|||.:||.||:|:.||.::|:||:.|||||.|:.:||||...|.|||||..|:|
 Frog   303 EASDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAESSDVA 367

  Fly   335 NAIIDGADCIMLSSEVAIGSFPKETVATCDTLCREAEKVLWFRDLFSDLVSEVRGELDAAHSLAI 399
            ||::|||||||||.|.|.|.:|.|:|.....:.||||..::.:.||.:|........|.....||
 Frog   368 NAVLDGADCIMLSGETAKGLYPLESVHMQHAIAREAEAAIYNQQLFEELRRVTPLTQDPTEVTAI 432

  Fly   400 AAVETAKRTNATLIIVLTTSGRSATLVSKFRPRCPIMAITRCERTARWVYLHRGVLPILYTLEPS 464
            .|||.:.:..|..|||||||||||..:|::|||.||:|:||..:.||..:|:|||.|:||.....
 Frog   433 GAVEASFKCCAGAIIVLTTSGRSAQHLSRYRPRAPIIAVTRNAQVARQAHLNRGVFPVLYREAQQ 497

  Fly   465 TDYATDVDARVQFAMTSAKKWGIIDDGDPIVIVSAWKDGGGFTNNVRVV 513
            ..:|.|||.||||.::..|..|.:...|.::||:.|:.|.||||.::||
 Frog   498 EAWADDVDRRVQFGISIGKVRGFLSKDDIVIIVTGWRPGSGFTNIMQVV 546

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2964	NP_608713.2	Pyruvate_Kinase	32..515	CDD:453956	217/486 (45%)
pklr	XP_031747000.1	Pyruvate_Kinase	60..548	CDD:238178	217/487 (45%)