Protein Alignment daw and GDF3

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_065685.1
• Gene: GDF3 / 9573
• HGNCID: 4218
• Length: 364
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 50/268 - (18%)
• Similarity: 117/268 - (43%)
• Gaps: 64/268 - (23%)

  Fly   366 SVNSTSAQQTIVVSEVEVDQQKDSKY-LSAAKTIAIQSVNVQDEWMKI-----------DIEWPI 418
            ::::...::.:.::::.:|...:|.| |.....:|:..|.....|.:.           .:.||
Human   112 NLSAIKEREQLTLAQLGLDLGPNSYYNLGPELELALFLVQEPHVWGQTTPKPGKMFVLRSVPWP- 175

  Fly   419 KHWISGHELSHLIQITCGGCDVSD---------MEEIISVDKD----YRP--------------F 456
                .|....:|:.:   ..|.:|         :|.::..|:|    ::|              .
Human   176 ----QGAVHFNLLDV---AKDWNDNPRKNFGLFLEILVKEDRDSGVNFQPEDTCARLRCSLHASL 233

  Fly   457 IVIDMQ-NRRRKSRQKRS------INCSSGMTECCREHLYISFRDIGWSNWILKPEGYNAYFCRG 514
            :|:.:. ::...||::|:      ::|.:   .|.|..|:|:|||:||..||:.|:|:.|.:|.|
Human   234 LVVTLNPDQCHPSRKRRAAIPVPKLSCKN---LCHRHQLFINFRDLGWHKWIIAPKGFMANYCHG 295

  Fly   515 SCSSVASVTQAASHHSSIMKILSTSGANKSLELVP--CCTAKQYSSLQLVVMDSSNTATVKTLPN 577
            .|....:::..:|:::.:..::......     :|  .|...:.|.:.::..|:::...::...:
Human   296 ECPFSLTISLNSSNYAFMQALMHAVDPE-----IPQAVCIPTKLSPISMLYQDNNDNVILRHYED 355

  Fly   578 MVVESCGC 585
            |||:.|||
Human   356 MVVDECGC 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	17/130 (13%)
		TGF_beta	481..585	CDD:278448	26/105 (25%)
GDF3	NP_065685.1	TGFb_propeptide	<109..220	CDD:279078	17/115 (15%)
		TGFB	264..364	CDD:214556	28/105 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810