Protein Alignment daw and INHBE

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_113667.1
• Gene: INHBE / 83729
• HGNCID: 24029
• Length: 350
• Species: Homo sapiens
• Alignment Length: 420
• Identity: 87/420 - (20%)
• Similarity: 146/420 - (34%)
• Gaps: 142/420 - (33%)

  Fly   221 ISVKSSAGGCPKCESNR---QVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFD 282
            :..:.:...||.|..::   |.|..       |.:|..|||||:.|.|...|::
Human    17 VRAQGTGSVCPSCGGSKLAPQAERA-------LVLELAKQQILDGLHLTSRPRI----------- 63

  Fly   283 GMTLSHPDDSTKNKELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDV 347
                :||....                 .|.|   ...|.:.|...|.
Human    64 ----THPPPQA-----------------ALTR---ALRRLQPGSVAPG----------------- 87

  Fly   348 STAVLWLFKNKQNRTDTASV-NSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMK 411
                     |.:.....|:| :||||..:::...:...:   |.:|..|:.           |:.
Human    88 ---------NGEEVISFATVTDSTSAYSSLLTFHLSTPR---SHHLYHARL-----------WLH 129

  Fly   412 IDIEWP------IKHW------------ISGHELSHL---------------------IQITC-- 435
            :....|      |..|            ::.|.:::|                     :|:.|
Human   130 VLPTLPGTLCLRIFRWGPRRRRQGSRTLLAEHHITNLGWHTLTLPSSGLRGEKSGVLKLQLDCRP 194

  Fly   436 --GGCDVSDM-EEIISVDKDYRPFIVIDMQ-NRRRKSR-QKRSINCSSGMTECCREHLYISFRDI 495
              |...|:.. ..::......:||:.:.:: |.....| ::|:..|......|||...|:.|:::
Human   195 LEGNSTVTGQPRRLLDTAGHQQPFLELKIRANEPGAGRARRRTPTCEPATPLCCRRDHYVDFQEL 259

  Fly   496 GWSNWILKPEGYNAYFCRGSCSS--VASVTQAASHHSSIMKILSTSG---ANKSLELVPCCTAKQ 555
            ||.:|||:||||...:|.|.|..  ..|...|||.||::..:|..:.   |:.|     ||....
Human   260 GWRDWILQPEGYQLNYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPASTS-----CCVPTA 319

  Fly   556 YSSLQLVVMDSSNTATVKTLPNMVVESCGC 585
            ...|.|:.:|.:.......:|:||||:|||
Human   320 RRPLSLLYLDHNGNVVKTDVPDMVVEACGC 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	39/258 (15%)
		TGF_beta	481..585	CDD:278448	37/108 (34%)
INHBE	NP_113667.1	TGF_beta	247..349	CDD:306518	37/106 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385831at2759
OrthoFinder	1	1.000	-	-		FOG0000887
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X477
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	8	7.880