Protein Alignment daw and Inhbe

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_114003.2
• Gene: Inhbe / 83711
• RGDID: 621196
• Length: 350
• Species: Rattus norvegicus
• Alignment Length: 406
• Identity: 96/406 - (23%)
• Similarity: 151/406 - (37%)
• Gaps: 118/406 - (29%)

  Fly   223 VKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLS 287
            |:|:...||.|.:    ..:|.:....|.:|..||||||.|.|...|:::.   |.|
  Rat    19 VQSTRSACPSCGA----PTLTPQGERALVLELAKQQILEGLHLTSRPRITR---PLP-------- 68

  Fly   288 HPDDSTKNKELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVST--- 349
               .:...:.|.....|:   .:..|||:|             :.|...||.:.:....|.|
  Rat    69 ---QAALTRALRRLQPRS---MVPGNREKV-------------ISFATSIDKSTSTYRSVLTFQL 114

  Fly   350 ----------AVLWLF-------------------KNKQNRTDTASVNSTSAQQTIVVSEVEVDQ 385
                      |.|||.                   :.:.:||..|...:||
  Rat   115 SPLWSHHLYHARLWLHVPPSFPATLYLRIFGCGTTRCRGSRTFLADYQTTS-------------- 165

  Fly   386 QKDSKYLSAAKTIAIQSVNVQDE---WMKIDIEW-PIKHWISGHELSHLIQITCGGCDVSDMEEI 446
                   |....:.:.|..::.|   ..|:.:|: |:....:...|..|:..|.|
  Rat   166 -------SGWHALTLPSSGLRSEESGVTKLQLEFRPLDLNSTTARLPRLLLDTAG---------- 213

  Fly   447 ISVDKDYRPFIVIDMQ-NRRRKSR-QKRSINCSSGMTECCREHLYISFRDIGWSNWILKPEGYNA 509
                 ..|||:.:.:: |.....| ::|:..|.|....|||...|:.|:::||.:|||:||||..
  Rat   214 -----QQRPFLELKIRANEPGAGRARRRTPTCESETPLCCRRDHYVDFQELGWRDWILQPEGYQL 273

  Fly   510 YFCRGSCSS--VASVTQAASHHSSIMKILSTSG---ANKSLELVPCCTAKQYSSLQLVVMDSSNT 569
            .:|.|.|..  ..|...|||.||::..:|..:.   |..|     ||.......|.|:.:|.:..
  Rat   274 NYCSGQCPPHLAGSPGIAASFHSAVFSLLKANNPWPAGSS-----CCVPTARRPLSLLYLDHNGN 333

  Fly   570 ATVKTLPNMVVESCGC 585
            .....:|:||||:|||
  Rat   334 VVKTDVPDMVVEACGC 349

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	46/249 (18%)
		TGF_beta	481..585	CDD:278448	37/108 (34%)
Inhbe	NP_114003.2	TGF_beta_INHBC_E	247..350	CDD:381676	39/108 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	116	1.000	Inparanoid score	I4723
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385831at2759
OrthoFinder	1	1.000	-	-		FOG0000887
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11848
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X477
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	10	9.930