DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment daw and gdf10b

DIOPT Version :9

Sequence 1:NP_001259967.1 Gene:daw / 33474 FlyBaseID:FBgn0031461 Length:586 Species:Drosophila melanogaster
Sequence 2:NP_001165060.2 Gene:gdf10b / 794493 ZFINID:ZDB-GENE-120316-1 Length:385 Species:Danio rerio


Alignment Length:122 Identity:27/122 - (22%)
Similarity:47/122 - (38%) Gaps:43/122 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   125 KVPRLWQHLMEQEEKAHRHVSPPVELPIMYGDAPEESSLSSDDH-----FDDLSPLDFVRNELMA 184
            |||.:.:::          |:.|...|....::|..||::|..|     :::...||||.:|:  
Zfish   272 KVPSILRNI----------VTRPYSTPYSQPESPHVSSMTSATHTPVLLYNNEPLLDFVHDEV-- 324

  Fly   185 EDQQNQEKDLDLDLDLDQQPETPIEPELPLGERNITISVKSSAGG--------CPKC 233
                  .|..|..::.:::...|.|.|.            .|:||        .|||
Zfish   325 ------SKTTDTLVNTEEEEPAPSEEEY------------DSSGGFGKSSDYDSPKC 363

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dawNP_001259967.1 TGFb_propeptide 244..458 CDD:279078
TGF_beta 481..585 CDD:278448
gdf10bNP_001165060.2 FN3 21..104 CDD:328772
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3900
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11848
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.000

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