Protein Alignment daw and TGFB3

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001316868.1
• Gene: TGFB3 / 7043
• HGNCID: 11769
• Length: 412
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 95/414 - (22%)
• Similarity: 169/414 - (40%)
• Gaps: 105/414 - (25%)

  Fly   241 HITEEQLTHLRIEFVKQQILEKLRLKESPKVSAV-ELP----------KPIFDGMTLSHPDDSTK 294
            ||.::     |:|.::.|||.||||...|:.:.: .:|          :.:.:.|.....:..|:
Human    34 HIKKK-----RVEAIRGQILSKLRLTSPPEPTVMTHVPYQVLALYNSTRELLEEMHGEREEGCTQ 93

  Fly   295 NKELDDYYARTSKKFILL-----NREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWL 354
            .....:|||:...||.::     :.|...|     .|...|..|.|.:...:
Human    94 ENTESEYYAKEIHKFDMIQGLAEHNELAVC-----PKGITSKVFRFNVSSVE------------- 140

  Fly   355 FKNKQN--RTD-----TASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQD--EWM 410
             ||:.|  |.:     ..:.:|...:|.|.:.::    .:..::::..:.|..:::..:.  ||:
Human   141 -KNRTNLFRAEFRVLRVPNPSSKRNEQRIELFQI----LRPDEHIAKQRYIGGKNLPTRGTAEWL 200

  Fly   411 KIDIEWPIKHWISGHELSHL---IQITC-------GGCDVSDMEEIISV---------------- 449
            ..|:...::.|:...| |:|   |.|.|       .|..:.::.|::.:
Human   201 SFDVTDTVREWLLRRE-SNLGLEISIHCPCHTFQPNGDILENIHEVMEIKFKGVDNEDDHGRGDL 264

  Fly   450 -----DKD-YRPFIVIDM----------QNRRRKSRQKRSINCSSGMTE-CCREHLYISFR-DIG 496
                 .|| :.|.:::.|          |..:||.|...:..|...:.| ||...|||.|| |:|
Human   265 GRLKKQKDHHNPHLILMMIPPHRLDNPGQGGQRKKRALDTNYCFRNLEENCCVRPLYIDFRQDLG 329

  Fly   497 WSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQL 561
            | .|:.:|:||.|.||.|.|..:.|   |.:.||:::.:.:|  .|......|||..:....|.:
Human   330 W-KWVHEPKGYYANFCSGPCPYLRS---ADTTHSTVLGLYNT--LNPEASASPCCVPQDLEPLTI 388

  Fly   562 VVMDSSNTATVKTLPNMVVESCGC 585
            :.. ...|..|:.|.||||:||.|
Human   389 LYY-VGRTPKVEQLSNMVVKSCKC 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	47/270 (17%)
		TGF_beta	481..585	CDD:278448	39/105 (37%)
TGFB3	NP_001316868.1	TGFb_propeptide	24..230	CDD:395559	44/224 (20%)
		Cell attachment site. /evidence=ECO:0000250|UniProtKB:P01137	261..263		0/1 (0%)
		TGF_beta_TGFB3	312..412	CDD:381656	40/107 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.910