Protein Alignment daw and BMP4

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001334841.1
• Gene: BMP4 / 652
• HGNCID: 1071
• Length: 455
• Species: Homo sapiens
• Alignment Length: 423
• Identity: 90/423 - (21%)
• Similarity: 161/423 - (38%)
• Gaps: 82/423 - (19%)

  Fly   204 PETPIEPELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKES 268
            |||        |::.:. .::..|||   ..|.:..|.:.:.:.|.|:        :..||.:..
Human    75 PET--------GKKKVA-EIQGHAGG---RRSGQSHELLRDFEATLLQ--------MFGLRRRPQ 119

  Fly   269 PKVSAVELPKPIFDGMTLSHPDDSTKN--------KELDDYYARTSKKFILLNREEVECNRARDG 325
            |..||| :|..:.|...|...::..:.        .|.....|.|.:.|    ..|.........
Human   120 PSKSAV-IPDYMRDLYRLQSGEEEEEQIHSTGLEYPERPASRANTVRSF----HHEEHLENIPGT 179

  Fly   326 KSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQ----------NRTDTASVNSTSAQQTIVVSE 380
            ..|.:..|.|.:... .|...:|:|.|.||:.:.          :|.:...|....|:   ||..
Human   180 SENSAFRFLFNLSSI-PENEVISSAELRLFREQVDQGPDWERGFHRINIYEVMKPPAE---VVPG 240

  Fly   381 VEVDQQKDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWIS--------GHELSHLIQI-TCG 436
            ..:.:..|::.:....|          .|...|:...:..|..        ..|::||.|. |..
Human   241 HLITRLLDTRLVHHNVT----------RWETFDVSPAVLRWTREKQPNYGLAIEVTHLHQTRTHQ 295

  Fly   437 GCDVSDMEEIISVDKDY---RPFIV----------IDMQNRRRKSRQKRSINCSSGMTECCREHL 488
            |..|.....:.....::   ||.:|          :..:.|.::|.:..|.........|.|..|
Human   296 GQHVRISRSLPQGSGNWAQLRPLLVTFGHDGRGHALTRRRRAKRSPKHHSQRARKKNKNCRRHSL 360

  Fly   489 YISFRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPCCTA 553
            |:.|.|:||::||:.|.||.|::|.|.|....:....:::|:.:..::::  .|.|:... ||..
Human   361 YVDFSDVGWNDWIVAPPGYQAFYCHGDCPFPLADHLNSTNHAIVQTLVNS--VNSSIPKA-CCVP 422

  Fly   554 KQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR 586
            .:.|::.::.:|..:...:|....||||.||||
Human   423 TELSAISMLYLDEYDKVVLKNYQEMVVEGCGCR 455

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	44/243 (18%)
		TGF_beta	481..585	CDD:278448	30/103 (29%)
BMP4	NP_001334841.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810