Protein Alignment daw and BMP2

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001191.1
• Gene: BMP2 / 650
• HGNCID: 1069
• Length: 396
• Species: Homo sapiens
• Alignment Length: 412
• Identity: 93/412 - (22%)
• Similarity: 172/412 - (41%)
• Gaps: 76/412 - (18%)

  Fly   210 PELPLGERNITISVKSSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAV 274
            ||  ||.|...    :::.|.|..:.:.:|  ::|.:|          ::|....||:.|..|..
Human    26 PE--LGRRKFA----AASSGRPSSQPSDEV--LSEFEL----------RLLSMFGLKQRPTPSRD 72

  Fly   275 ELPKPIFDGMTLSH---PDDSTKNKELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFK 336
            .:..|....:...|   |.....:..|:...:|.:......:.|.:|......||:  :..|.|.
Human    73 AVVPPYMLDLYRRHSGQPGSPAPDHRLERAASRANTVRSFHHEESLEELPETSGKT--TRRFFFN 135

  Fly   337 IDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQ 401
            :.....|.| :::|.|.:|:.:.   ..|..|::|....|.:.|:......:||: ...:.:..:
Human   136 LSSIPTEEF-ITSAELQVFREQM---QDALGNNSSFHHRINIYEIIKPATANSKF-PVTRLLDTR 195

  Fly   402 SVNVQ-DEWMKIDIEWPIKHWISGHELSHLIQITCGGCDVSDMEEIISVDKDY------------ 453
            .||.. ..|...|:...:..|.:....:|...:     :|:.:||...|.|.:
Human   196 LVNQNASRWESFDVTPAVMRWTAQGHANHGFVV-----EVAHLEEKQGVSKRHVRISRSLHQDEH 255

  Fly   454 -----RPFIVI-----------DMQNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGWSNWIL 502
                 ||.:|.           ..:.|:.|.:|::.:..|     |.|..||:.|.|:||::||:
Human   256 SWSQIRPLLVTFGHDGKGHPLHKREKRQAKHKQRKRLKSS-----CKRHPLYVDFSDVGWNDWIV 315

  Fly   503 KPEGYNAYFCRGSCS-SVASVTQAASHHSSIMKILSTSGANKSLELVP--CCTAKQYSSLQLVVM 564
            .|.||:|::|.|.|. .:|....:.:|  :|::.|..|..:|    :|  ||...:.|::.::.:
Human   316 APPGYHAFYCHGECPFPLADHLNSTNH--AIVQTLVNSVNSK----IPKACCVPTELSAISMLYL 374

  Fly   565 DSSNTATVKTLPNMVVESCGCR 586
            |.:....:|...:||||.||||
Human   375 DENEKVVLKNYQDMVVEGCGCR 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	43/234 (18%)
		TGF_beta	481..585	CDD:278448	34/106 (32%)
BMP2	NP_001191.1	TGFb_propeptide	37..267	CDD:279078	47/253 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	84..121		6/36 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	271..293		3/21 (14%)
		TGFB	296..396	CDD:214556	35/105 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810