Protein Alignment daw and Tgfb1

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_067589.1
• Gene: Tgfb1 / 59086
• RGDID: 69051
• Length: 390
• Species: Rattus norvegicus
• Alignment Length: 401
• Identity: 99/401 - (24%)
• Similarity: 169/401 - (42%)
• Gaps: 80/401 - (19%)

  Fly   227 AGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPDD 291
            |.|...|::      |..|.:...|||.::.|||.||||...|....|. |.|:.:.:...:  :
  Rat    27 AAGLSTCKT------IDMELVKRKRIEAIRGQILSKLRLASPPSQGEVP-PGPLPEAVLALY--N 82

  Fly   292 STKNKELD-----------DYYARTSKKFILLNREEVECNRARDGKSNPSMCF-TFKIDDADAEG 344
            ||:::...           ||||:...:.::::|.....::.:|...:..|.| |..|.:|..|.
  Rat    83 STRDRVAGESADPEPEPEADYYAKEVTRVLMVDRNNAIYDKTKDITHSIYMFFNTSDIREAVPEP 147

  Fly   345 FDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQKDS---KYLSAAKTIAIQSVNVQ 406
            ..:|.|.|.|.:.|                :.|...||:.|:..:   :||..    .:.:....
  Rat   148 PLLSRAELRLQRFK----------------STVEQHVELYQKYSNNSWRYLGN----RLLTPTDT 192

  Fly   407 DEWMKIDIEWPIKHW------ISGHELS---------HLIQITCGGCDVSDMEEIISVDKDYRPF 456
            .||:..|:...::.|      |.|...|         :::.:...|.......::.::....|||
  Rat   193 PEWLSFDVTGVVRQWLNQGDGIQGFRFSAHCSCDSKDNVLHVEINGISPKRRGDLGTIHDMNRPF 257

  Fly   457 IV-----IDMQNRRRKSRQKRSIN---C-SSGMTECCREHLYISFR-DIGWSNWILKPEGYNAYF 511
            ::     ::.......||.:|:::   | ||....||...|||.|| |:|| .||.:|:||:|.|
  Rat   258 LLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYIDFRKDLGW-KWIHEPKGYHANF 321

  Fly   512 CRGSCSSVASVTQAASHHSSIMKILS--TSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKT 574
            |.|.|..:.|:.   :.:|.::.:.:  ..||:.|    |||..:....|.:|.. ......|:.
  Rat   322 CLGPCPYIWSLD---TQYSKVLALYNQHNPGASAS----PCCVPQALEPLPIVYY-VGRKPKVEQ 378

  Fly   575 LPNMVVESCGC 585
            |.||:|.||.|
  Rat   379 LSNMIVRSCKC 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	51/243 (21%)
		TGF_beta	481..585	CDD:278448	37/106 (35%)
Tgfb1	NP_067589.1	TGFb_propeptide	30..261	CDD:395559	53/259 (20%)
		Straightjacket domain. /evidence=ECO:0000250|UniProtKB:P07200	30..74		17/50 (34%)
		Arm domain. /evidence=ECO:0000250|UniProtKB:P07200	75..271		36/217 (17%)
		Bowtie tail. /evidence=ECO:0000250|UniProtKB:P01137	226..252		1/25 (4%)
		Cell attachment site. /evidence=ECO:0000255	244..246		0/1 (0%)
		TGF_beta_TGFB1	292..390	CDD:381654	38/107 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.870