Protein Alignment daw and tgfb5

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: XP_021336789.1
• Gene: tgfb5 / 559723
• ZFINID: ZDB-GENE-130425-3
• Length: 414
• Species: Danio rerio
• Alignment Length: 444
• Identity: 114/444 - (25%)
• Similarity: 179/444 - (40%)
• Gaps: 109/444 - (24%)

  Fly   218 NITISVK---SSAGGCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKP 279
            |:|:.|.   :||.|...|.|....:|.::      |||.|:.|||.|||::..|...|...|:|
Zfish     5 NLTLLVLKLFASAEGFSTCHSYNLDDHKSK------RIEAVRGQILSKLRIRSPPDPEASPTPQP 63

  Fly   280 IFDGMTLSHPDDSTKN--KEL--------------DDYYARTSKKFILLNREEVECNRARDGKSN 328
            :...:.|.:  :|||.  ||.              :||||:..::..::.. ..:.|....|..:
Zfish    64 VPAEVMLLY--NSTKELLKERARHAEAACERESSEEDYYAKEVQRVNMMPL-RTDTNSISPGPQS 125

  Fly   329 PSMCFTFKIDDADAEGFDV-------STAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQ 386
            |    .|:|     .||||       ||.|         :.:.....:.:.|.......||:.|.
Zfish   126 P----YFRI-----VGFDVTNVERNSSTLV---------KAEFRIFRAPNPQARATEQRVEIYQI 172

  Fly   387 KDSKYLSAAKTIAIQSVNVQDE----WMKIDIEWPIKHWISGHE--LSHLIQITCGGCDV----- 440
            ..|:.::|.....|.|..|:..    |:.:|:...:|.|::..|  |...|.:.|..|..
Zfish   173 LKSEDVTAPSQRYIDSRTVEPRAKGAWLSVDVTETVKEWMAFRERNLGLKISVHCPCCTFVPSTN 237

  Fly   441 ----SDMEEI----ISVDKDY-------------------RPFIVID------MQNRRRKSRQKR 472
                :..||:    ..:|.|.                   .|.:::.      :.:..:|:|:||
Zfish   238 NIVPNKSEELEARFAGIDDDLIKQTRKPGVTKGQIEFSTKTPHLILTLLPTDRLDSPIKKTRKKR 302

  Fly   473 SIN----CSSGMTECCREHLYISF-RDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSI 532
            |..    |:.....||...|||.| ||:.| .||.:|:||.|.||.|:|..:.|   |.:|::.|
Zfish   303 SAADTSICTRNDQGCCLRSLYIDFRRDLNW-KWIHEPKGYKANFCAGNCPYLWS---ADNHYNMI 363

  Fly   533 MKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR 586
            :.:.:.  .|......|||..:....|.:|.. ...|..|:.|.||||.||.||
Zfish   364 LPLYNK--MNPEASASPCCVPQDLEPLTIVYF-LGRTPRVEQLSNMVVRSCKCR 414

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	59/274 (22%)
		TGF_beta	481..585	CDD:278448	38/104 (37%)
tgfb5	XP_021336789.1	TGFb_propeptide	21..229	CDD:307025	56/234 (24%)
		TGF_beta	317..413	CDD:306518	38/102 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	45	1.000	Domainoid score	I12159
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	5	4.870