Protein Alignment daw and Lefty1

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001102550.1
• Gene: Lefty1 / 498299
• RGDID: 1561867
• Length: 368
• Species: Rattus norvegicus
• Alignment Length: 405
• Identity: 91/405 - (22%)
• Similarity: 140/405 - (34%)
• Gaps: 128/405 - (31%)

  Fly   240 EHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIFDGMT------------LSHPDDS 292
            |.:|.||        |...:|::|||...|     .|.|...:||.            |.|..||
  Rat    20 EALTGEQ--------VLGSLLQQLRLDRPP-----VLDKADVEGMVIPSHVRAQYVALLQHSHDS 71

  Fly   293 -TKNKELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFK 356
             ::.|.....:...:.:|::              ....|....|.::.......::..|||.||:
  Rat    72 RSRGKRFSQNFREVAGRFLV--------------SETSSHLLVFGMEQRLPPNSELVQAVLRLFQ 122

  Fly   357 NKQNRT-----DTASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQS--VNVQDE-WMKID 413
            ....||     ...|.:|..|:.||.......|        .:.:|..|.|  |::.:. |...|
  Rat   123 EPVPRTALRRQKRLSPHSARARVTIEWLRFRED--------GSNRTALIDSRLVSIHESGWKVFD 179

  Fly   414 IEWPIKHW-------------------------ISGHELSHL-IQITCGGCDVSDME-EIISVD- 450
            :...:..|                         .|.|:|... .|.|..|..:.:.: |:.::|
  Rat   180 VTEAVNFWQQLSRPRQPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGLGEPQLELHTLDL 244

  Fly   451 KDYRPFIVIDMQNRRRKSRQKRSINC------SSGMTECCREHLYISFRDIGWS-NWILKPEGYN 508
            |||      ..|.           ||      :.| |.|||:.:|:..:.:.|: ||||:|.|:.
  Rat   245 KDY------GAQG-----------NCDPETPVTEG-TRCCRQEMYLDLQGMKWAENWILEPPGFL 291

  Fly   509 AYFCRGSCSSVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVM---DSSNTA 570
            .|.|.|||         .....|:.......|..:       |.|.:.:||.|:|.   |.....
  Rat   292 TYECVGSC---------LQPPESLTIRWPFLGPRQ-------CVASEMTSLPLIVSIKEDGRTRP 340

  Fly   571 TVKTLPNMVVESCGC 585
            .|.:||||.|:.|.|
  Rat   341 QVVSLPNMRVQRCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	51/262 (19%)
		TGF_beta	481..585	CDD:278448	33/107 (31%)
Lefty1	NP_001102550.1	TGFb_propeptide	29..211	CDD:413528	37/208 (18%)
		TGF_beta_LEFTY1_2	264..355	CDD:381636	32/106 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910