Protein Alignment daw and gdf3

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_001007905.1
• Gene: gdf3 / 493288
• XenbaseID: XB-GENE-487309
• Length: 350
• Species: Xenopus tropicalis
• Alignment Length: 378
• Identity: 81/378 - (21%)
• Similarity: 149/378 - (39%)
• Gaps: 89/378 - (23%)

  Fly   252 IEFVKQQILEKLRLKESPKVSAVELPKPIFDGMTLSHPDDSTKNKELDDYYARTSKKFILLNREE 316
            :.|.::.:|:.|.|...|...|   |.|:              .|.|.|.:.:.      :|::.
 Frog    19 LTFQERMLLKALGLNTRPNPIA---PGPV--------------PKSLRDIFEKG------INKDN 60

  Fly   317 --------VECNRARDGKS----------NPSMC---FTFKIDDADAEGFDVSTAVLWLFKNKQN 360
                    |..|..|..:.          ..|:|   |.|         ||:|..     :||:.
 Frog    61 PCMMEGFGVPGNIVRSYRDQGPVAAMEEPQESLCLKKFLF---------FDLSAV-----ENKEQ 111

  Fly   361 RT-----DTASVNSTSAQQ-------TIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMKID 413
            .|     .....||...||       |:.:|...:.:.|.::.|..:::..:...::.....|:.
 Frog   112 LTLGQLEIKFKHNSYYGQQFHLRLYRTLQLSLKGMRESKMNRKLLVSQSFRLLHKSLYFNLTKVA 176

  Fly   414 IEW--PIKHWISGHELSHLIQITCGGCDVSDMEEIISVDKDYRPFIVIDM------QNRRRKSRQ 470
            .:|  |.|:      :..|::|........| ....:|.:..:.||...:      .:..:..|.
 Frog   177 KDWKTPEKN------MGLLLEIYASSKLAGD-NRSFAVCEPIQSFIYTSLLTVSLDPSSCKTPRA 234

  Fly   471 KRSINCS--SGMTECCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIM 533
            |||.:.|  :....|.:..|||.|:|:||.||::.|.||.|.:|.|.|....:.....::| :::
 Frog   235 KRSTHSSPPTPSNICKKRRLYIDFKDVGWQNWVIAPRGYMANYCYGECPYPLTEMLRGTNH-AVL 298

  Fly   534 KILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGCR 586
            :.|..|...:|..| |||...:.|.:.::..|:::...::...:|||:.|||:
 Frog   299 QTLVHSVEPESTPL-PCCAPTKLSPISMLYYDNNDNVVLRHYEDMVVDECGCK 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	31/101 (31%)
gdf3	NP_001007905.1	TGFb_propeptide	23..197	CDD:480997	38/216 (18%)
		TGF_beta_GDF1_3_like	249..350	CDD:381642	32/102 (31%)