Protein Alignment daw and Actbeta

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_651942.2
• Gene: Actbeta / 43826
• FlyBaseID: FBgn0024913
• Length: 946
• Species: Drosophila melanogaster
• Alignment Length: 727
• Identity: 146/727 - (20%)
• Similarity: 257/727 - (35%)
• Gaps: 228/727 - (31%)

  Fly    10 LLVCLALENRNVYNRLHARSHPSSRGDILRPHPKHQPHPHVQ----HTSQQLQQQHHIRQQRSRQ 70
            |:.|..:.:.|.|    |.:..|.:|..| .|...:|:.:..    ||...:..::|.....:::
  Fly   296 LINCNGISSSNYY----ASNLESHKGCTL-CHESGKPNIYTDKDNPHTDYNIYNKYHSNNNFNKK 355

  Fly    71 LK--HLEPDPTSEEDDVPITKREYYARLRRHVIHKRQHLLQQELSYNHPGSHSEQLKVPR--LWQ 131
            ..  |....|:.|              :|...| |||.|.:..||:....||    .:|:  :|:
  Fly   356 TNQPHNNIAPSDE--------------VRLESI-KRQILTKLGLSHKPNVSH----PLPKQFIWE 401

  Fly   132 ---------------------HLMEQEEKAHRHVSPPVELPIMYGDAPEESSLSSDDHFDDLSPL 175
                                 :|.::..|.....||...|....|...::.|.....|....||.
  Fly   402 TIYRVDGGRMIPNNAFGSSGKNLDQKTIKLRAFASPGSHLFNGRGGRTDQRSERDPSHHKYRSPF 466

  Fly   176 DF-------------VRNELMAE-DQQN-------QEKDLDLDLDLDQQPETPIEPELPLGERNI 219
            ||             :||..:.. |::|       :.:.|.::..:...|
  Fly   467 DFTFNISKNNVYGKVLRNRSLERIDKKNSFLNGWTENRQLKINSQIASMP--------------- 516

  Fly   220 TISVKSSAGGCP---KCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPKPIF 281
             |.:||.....|   |..:.|:|..|...|             :.:..||:|        ..||.
  Fly   517 -IELKSHHNSSPKELKSGAVRKVNGINGTQ-------------MNENALKKS--------TYPID 559

  Fly   282 DGMTLSHPDDSTKNKEL--------DDYYARTSKKFILLNREEVECNRARDGKSN----PSM--- 331
            ...::.:...:.||.|:        :||..:|..|           ||..:|:|:    |::
  Fly   560 INHSIDNKTHTGKNGEMSHNDYEYFNDYSVQTHDK-----------NRYHEGRSSIGYQPAIHNI 613

  Fly   332 ----------CFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSE------ 380
                      .|....::.|.|.|..:|..:..|..:..:.....:...|||...|.|:
  Fly   614 EYENQKGHHESFADDHENIDHEDFFGNTQEIITFAEEGTQYRQYRILEFSAQNRRVPSQKLSIRS 678

  Fly   381 ----VEVDQQKDSKYLSAAKTIAIQ---------------------------SVNVQDE------ 408
                :.:| :..|.::..||::..:                           |:|:.::
  Fly   679 AQIHIRID-KPHSLWIEKAKSLPEKHLLNTKRKWGANKPHHRIKIWVFQLSTSINITEKGIDKAI 742

  Fly   409 --------------WMKIDIEWPIKHWI--SGHELSHLIQITCGGCDVSDMEEIISVDK------ 451
                          |.|.|:...|:.|.  :.||...|: |.|.||.......:....|
  Fly   743 IFRASFQVDPKNLGWQKFDLTDTIREWYGHTSHEKLRLL-IDCTGCGGRYSLHLFQTSKLRGNSS 806

  Fly   452 DY------RPFIVIDMQNRRRKSRQKRSINCSSGMT-ECCREHLYISFRDIGWSNWILKPEGYNA 509
            ||      |||:|:..::.|.:..::|:::|...:. :||:|..|:||:.:||.:||:.|.||.|
  Fly   807 DYLSTNPNRPFLVLHTESSRTRRVRRRAVDCGGALNGQCCKESFYVSFKALGWDDWIIAPRGYFA 871

  Fly   510 YFCRGSCS-SVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVK 573
            .:|||.|: |..:.....:.|:..::.....|....:.  |||...::||:.|:......... :
  Fly   872 NYCRGDCTGSFRTPDTFQTFHAHFIEEYRKMGLMNGMR--PCCAPIKFSSMSLIYYGDDGIIK-R 933

  Fly   574 TLPNMVVESCGC 585
            .||.|||:.|||
  Fly   934 DLPKMVVDECGC 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	53/309 (17%)
		TGF_beta	481..585	CDD:278448	33/105 (31%)
Actbeta	NP_651942.2	TGFb_propeptide	370..>509	CDD:279078	29/143 (20%)
		TGF_beta	843..945	CDD:278448	33/104 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385831at2759
OrthoFinder	1	1.000	-	-		FOG0000887
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X477
	6	5.920