Protein Alignment daw and INHBC

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_005529.1
• Gene: INHBC / 3626
• HGNCID: 6068
• Length: 352
• Species: Homo sapiens
• Alignment Length: 398
• Identity: 98/398 - (24%)
• Similarity: 155/398 - (38%)
• Gaps: 94/398 - (23%)

  Fly   220 TISVKSSAGGCPKC-------ESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELP 277
            |::...:.|.||.|       ||.|:           |.::..|:.||:||.|.:.|     .|.
Human    16 TVATPRAGGQCPACGGPTLELESQRE-----------LLLDLAKRSILDKLHLTQRP-----TLN 64

  Fly   278 KPIFDG---MTLSHPDDSTKNKELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFKID- 338
            :|:...   ..|.|.....:...|:|            |||: ||......::..|.....::|
Human    65 RPVSRAALRTALQHLHGVPQGALLED------------NREQ-ECEIISFAETGLSTINQTRLDF 116

  Fly   339 ----DADAEGFDVSTAVLWLF-KNKQNRTDTASV----------NSTSAQQTIVVSEVEVDQQKD 388
                |..|...:|..|.|..| :...|.|.|..|          |.|.|.|.:    :|||
Human   117 HFSSDRTAGDREVQQASLMFFVQLPSNTTWTLKVRVLVLGPHNTNLTLATQYL----LEVD---- 173

  Fly   389 SKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWIS-GHELSHLI---QITCGGCDVSDMEEIISV 449
                             ...|.::.:....:...| ||....|:   |:.        ...:|..
Human   174 -----------------ASGWHQLPLGPEAQAACSQGHLTLELVLEGQVA--------QSSVILG 213

  Fly   450 DKDYRPFIVIDMQNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGWSNWILKPEGYNAYFCRG 514
            ...:|||:...::...:....:|.|:|..|...|||:..::.||:|||.:||::||||...||.|
Human   214 GAAHRPFVAARVRVGGKHQIHRRGIDCQGGSRMCCRQEFFVDFREIGWHDWIIQPEGYAMNFCIG 278

  Fly   515 SCS-SVASVTQ-AASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDSSNTATVKTLPN 577
            .|. .:|.:.. |||.|::::.:|..:.|..:.....||.......|.|:..|..:......:|:
Human   279 QCPLHIAGMPGIAASFHTAVLNLLKANTAAGTTGGGSCCVPTARRPLSLLYYDRDSNIVKTDIPD 343

  Fly   578 MVVESCGC 585
            ||||:|||
Human   344 MVVEACGC 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	36/103 (35%)
INHBC	NP_005529.1	TGF_beta_INHBC_E	247..352	CDD:381676	38/105 (36%)