Protein Alignment daw and INHBB

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_002184.2
• Gene: INHBB / 3625
• HGNCID: 6067
• Length: 407
• Species: Homo sapiens
• Alignment Length: 421
• Identity: 97/421 - (23%)
• Similarity: 162/421 - (38%)
• Gaps: 86/421 - (20%)

  Fly   204 PETPIEPELPLGERNITISVKSSAGG----CPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLR 264
            |.||..|..|        ....|.||    |..|...|:.|.:.......|  |.||:.||.:|:
Human    33 PPTPAAPPPP--------PPPGSPGGSQDTCTSCGGFRRPEELGRVDGDFL--EAVKRHILSRLQ 87

  Fly   265 LKESPKVSAVELPK-----------------------PIFDGMTLSHPDDSTKNKELDDYYARTS 306
            ::..|.::.. :||                       |..||......|...:..|:.. :|.|
Human    88 MRGRPNITHA-VPKAAMVTALRKLHAGKVREDGRVEIPHLDGHASPGADGQERVSEIIS-FAET- 149

  Fly   307 KKFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTS 371
                             ||.::..:...|.|.:...:...|..|.|||:...     ...|....
Human   150 -----------------DGLASSRVRLYFFISNEGNQNLFVVQASLWLYLKL-----LPYVLEKG 192

  Fly   372 AQQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMKIDIEWPIKHWISGHELSHLIQITCG 436
            :::.:.|.....:|....::....|.:.::    :..|....:...|:......|....:.:.|.
Human   193 SRRKVRVKVYFQEQGHGDRWNMVEKRVDLK----RSGWHTFPLTEAIQALFERGERRLNLDVQCD 253

  Fly   437 GCDVSDMEEIISV-------DKDYRPFIVIDMQNRRRKSR---QKRSINCSSGMTECCREHLYIS 491
            .|     :|:..|       ::.:|||:|:  |.|...||   :||.:.|......|||:..:|.
Human   254 SC-----QELAVVPVFVDPGEESHRPFVVV--QARLGDSRHRIRKRGLECDGRTNLCCRQQFFID 311

  Fly   492 FRDIGWSNWILKPEGYNAYFCRGSCSS-VASVT-QAASHHSSIMKILSTSGANKSLELVPCCTAK 554
            ||.|||::||:.|.||...:|.|||.: :|.|. .|:|.|::::......|.|.. .:..||...
Human   312 FRLIGWNDWIIAPTGYYGNYCEGSCPAYLAGVPGSASSFHTAVVNQYRMRGLNPG-TVNSCCIPT 375

  Fly   555 QYSSLQLVVMDSSNTATVKTLPNMVVESCGC 585
            :.|::.::..|.......:.:|||:||.|||
Human   376 KLSTMSMLYFDDEYNIVKRDVPNMIVEECGC 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	40/243 (16%)
		TGF_beta	481..585	CDD:278448	35/105 (33%)
INHBB	NP_002184.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	26..62		10/36 (28%)
		TGFb_propeptide	57..278	CDD:279078	43/256 (17%)
		TGFB	303..406	CDD:214556	35/103 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1385831at2759
OrthoFinder	1	1.000	-	-		FOG0000887
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X477
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.920