Protein Alignment daw and INHA

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_002182.1
• Gene: INHA / 3623
• HGNCID: 6065
• Length: 366
• Species: Homo sapiens
• Alignment Length: 282
• Identity: 62/282 - (21%)
• Similarity: 98/282 - (34%)
• Gaps: 85/282 - (30%)

  Fly   347 VSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQSVNVQDEWMK 411
            |::|.|| |....:|..||:.||:.....::.             ||....:|:.        |.
Human   126 VTSAQLW-FHTGLDRQGTAASNSSEPLLGLLA-------------LSPGGPVAVP--------MS 168

  Fly   412 IDIEWPIKHWISGH-------ELSH---LIQITCGGCDVSDMEEIISVDKDYRPFIVIDMQNRRR 466
            :....|  ||...|       .|:|   ::.:.|..|..|...|.       .||:|...:.|..
Human   169 LGHAPP--HWAVLHLATSALSLLTHPVLVLLLRCPLCTCSARPEA-------TPFLVAHTRTRPP 224

  Fly   467 K--SRQKRSINCSS-------------------GMTECCREHLYISFRDIGWSNWILKPEGYNAY 510
            .  .|.:||....|                   ....|.|..|.|||:::||..||:.|..:..:
Human   225 SGGERARRSTPLMSWPWSPSALRLLQRPPEEPAAHANCHRVALNISFQELGWERWIVYPPSFIFH 289

  Fly   511 FCRGSCS---------SVASVTQAASHHSSIMKILSTSGANKSLELVPCCTAKQYSSLQLVVMDS 566
            :|.|.|.         .|.......:...|::     .||.      |||.|...:...|.|..:
Human   290 YCHGGCGLHIPPNLSLPVPGAPPTPAQPYSLL-----PGAQ------PCCAALPGTMRPLHVRTT 343

  Fly   567 SN---TATVKTLPNMVVESCGC 585
            |:   :...:|:||::.:.|.|
Human   344 SDGGYSFKYETVPNLLTQHCAC 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	29/113 (26%)
INHA	NP_002182.1	TGF_beta_SF	261..366	CDD:477357	30/116 (26%)