Protein Alignment daw and BMP8A

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_861525.2
• Gene: BMP8A / 353500
• HGNCID: 21650
• Length: 402
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 105/438 - (23%)
• Similarity: 174/438 - (39%)
• Gaps: 108/438 - (24%)

  Fly   213 PLGERNITISVKSSAG-------GCPKCESNRQVEHITEEQLTHLRIEFVKQQILEKLRLKESPK 270
            ||....:|:......|       |||            :.:|.......|:::||..|.|...|:
Human     7 PLWLLGLTLCALGGGGPGLRPPPGCP------------QRRLGARERRDVQREILAVLGLPGRPR 59

  Fly   271 ----VSAVELP--KPIFDGMTLSHP---DDSTKNKELDDYYARTSKKFILLNREEVECNRARDGK 326
                .:|..||  .|:| .:.|.|.   ||.......:....|.......:|.  ||.:||. |.
Human    60 PRAPPAASRLPASAPLF-MLDLYHAMAGDDDEDGAPAEQRLGRADLVMSFVNM--VERDRAL-GH 120

  Fly   327 SNPSMC-FTFKIDDADAEGFDVSTAVLWLFKNKQNRTDTASVNSTSAQQTIVVSEVEVDQQKDSK 390
            ..|... |.|.:....| |..|:.|...::|       ..|::..:  :|:.||..:|.|::.::
Human   121 QEPHWKEFRFDLTQIPA-GEAVTAAEFRIYK-------VPSIHLLN--RTLHVSMFQVVQEQSNR 175

  Fly   391 YLSAAKTIAIQSVNVQDE-WMKIDIE-----WPIK-HWISGHELSHLIQITCGGCDVSDMEEIIS 448
            . |....:.:|::...|| |:.:|:.     |.:| |...|..|            ..:.|:..|
Human   176 E-SDLFFLDLQTLRAGDEGWLVLDVTAASDCWLLKRHKDLGLRL------------YVETEDGHS 227

  Fly   449 VD------------KDYRPFIVIDMQN--------------RRRKSRQKR-------------SI 474
            ||            :..:||:|...:.              |||:.::..             .:
Human   228 VDPGLAGLLGQRAPRSQQPFVVTFFRASPSPIRTPRAVRPLRRRQPKKSNELPQANRLPGIFDDV 292

  Fly   475 NCSSGMTECCREHLYISFRDIGWSNWILKPEGYNAYFCRGSCSSVASVTQAASHHSSIMKILSTS 539
            ..|.|...|.|..||:||:|:||.:|::.|:||:||:|.|.||........|::|:.:..::...
Human   293 RGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGECSFPLDSCMNATNHAILQSLVHLM 357

  Fly   540 GANKSLELVP--CCTAKQYSSLQLVVMDSSNTATVKTLPNMVVESCGC 585
            ..|    .||  ||...:.|:..::..||||...::...||||::|||
Human   358 KPN----AVPKACCAPTKLSATSVLYYDSSNNVILRKHRNMVVKACGC 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	54/242 (22%)
		TGF_beta	481..585	CDD:278448	36/105 (34%)
BMP8A	NP_861525.2	TGFb_propeptide	33..251	CDD:279078	55/244 (23%)
		TGF_beta	299..401	CDD:278448	36/105 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810