Protein Alignment daw and Lefty2

DIOPT Version :10

• Sequence 1: NP_523461.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_796073.1
• Gene: Lefty2 / 320202
• MGIID: 2443573
• Length: 368
• Species: Mus musculus
• Alignment Length: 394
• Identity: 81/394 - (20%)
• Similarity: 147/394 - (37%)
• Gaps: 110/394 - (27%)

  Fly   242 ITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPK------------PIFDGMTLSHPDDSTK 294
            :||||        |...:|::|:|.::|.:.:.::.:            .:..|   ||.|.| :
Mouse    22 MTEEQ--------VLSSLLQQLQLSQAPTLDSADVEEMAIPTHVRSQYVALLQG---SHADRS-R 74

  Fly   295 NKELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQ 359
            .|.....:...:.:|::              ....:....|.::.......::..|||.||:...
Mouse    75 GKRFSQNFREVAGRFLM--------------SETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPV 125

  Fly   360 NRT-----DTASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQS--VNVQDE-WMKIDIEW 416
            .||     :..|.:|..|:.||....|..|        .:.:|..|.|  |::.:. |...|:..
Mouse   126 PRTALRRFERLSPHSARARVTIEWLRVRED--------GSNRTALIDSRLVSIHESGWKAFDVTE 182

  Fly   417 PIKHWISGHELSH-----LIQITCG----GCDVSDMEEIISVDKDYRP-----------FIVIDM 461
            .:..|   .:||.     |:|::..    |.......:::.......|           ...:|:
Mouse   183 AVNFW---QQLSRPRQPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGQGEPQLELHTLDL 244

  Fly   462 QNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGWS-NWILKPEGYNAYFCRGSCSSVASVTQA 525
            ::...:......:..:.| |.|||:.:|:..:.:.|: ||||:|.|:..|.|.|||..:.
Mouse   245 KDYGAQGNCDPEVPVTEG-TRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQLP----- 303

  Fly   526 ASHHSSIMKILSTSGANKSLE-----LVP-CCTAKQYSSLQLVVMDSSNTAT---VKTLPNMVVE 581
                             :||.     |.| .|.|.:.:||.::|.......|   |.:||||.|:
Mouse   304 -----------------ESLTIGWPFLGPRQCVASEMTSLPMIVSVKEGGRTRPQVVSLPNMRVQ 351

  Fly   582 SCGC 585
            :|.|
Mouse   352 TCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_523461.1	TGF_beta_INHB	483..585	CDD:381630	33/111 (30%)
Lefty2	NP_796073.1	TGFb_propeptide	<106..203	CDD:480997	25/107 (23%)
		TGF_beta_LEFTY1_2	264..355	CDD:381636	33/112 (29%)