Protein Alignment daw and Lefty2

DIOPT Version :9

• Sequence 1: NP_001259967.1
• Gene: daw / 33474
• FlyBaseID: FBgn0031461
• Length: 586
• Species: Drosophila melanogaster
• Sequence 2: NP_796073.1
• Gene: Lefty2 / 320202
• MGIID: 2443573
• Length: 368
• Species: Mus musculus
• Alignment Length: 394
• Identity: 81/394 - (20%)
• Similarity: 147/394 - (37%)
• Gaps: 110/394 - (27%)

  Fly   242 ITEEQLTHLRIEFVKQQILEKLRLKESPKVSAVELPK------------PIFDGMTLSHPDDSTK 294
            :||||        |...:|::|:|.::|.:.:.::.:            .:..|   ||.|.| :
Mouse    22 MTEEQ--------VLSSLLQQLQLSQAPTLDSADVEEMAIPTHVRSQYVALLQG---SHADRS-R 74

  Fly   295 NKELDDYYARTSKKFILLNREEVECNRARDGKSNPSMCFTFKIDDADAEGFDVSTAVLWLFKNKQ 359
            .|.....:...:.:|::              ....:....|.::.......::..|||.||:...
Mouse    75 GKRFSQNFREVAGRFLM--------------SETSTHLLVFGMEQRLPPNSELVQAVLRLFQEPV 125

  Fly   360 NRT-----DTASVNSTSAQQTIVVSEVEVDQQKDSKYLSAAKTIAIQS--VNVQDE-WMKIDIEW 416
            .||     :..|.:|..|:.||....|..|        .:.:|..|.|  |::.:. |...|:..
Mouse   126 PRTALRRFERLSPHSARARVTIEWLRVRED--------GSNRTALIDSRLVSIHESGWKAFDVTE 182

  Fly   417 PIKHWISGHELSH-----LIQITCG----GCDVSDMEEIISVDKDYRP-----------FIVIDM 461
            .:..|   .:||.     |:|::..    |.......:::.......|           ...:|:
Mouse   183 AVNFW---QQLSRPRQPLLLQVSVQREHLGPGTWSAHKLVRFAAQGTPDGKGQGEPQLELHTLDL 244

  Fly   462 QNRRRKSRQKRSINCSSGMTECCREHLYISFRDIGWS-NWILKPEGYNAYFCRGSCSSVASVTQA 525
            ::...:......:..:.| |.|||:.:|:..:.:.|: ||||:|.|:..|.|.|||..:.
Mouse   245 KDYGAQGNCDPEVPVTEG-TRCCRQEMYLDLQGMKWAENWILEPPGFLTYECVGSCLQLP----- 303

  Fly   526 ASHHSSIMKILSTSGANKSLE-----LVP-CCTAKQYSSLQLVVMDSSNTAT---VKTLPNMVVE 581
                             :||.     |.| .|.|.:.:||.::|.......|   |.:||||.|:
Mouse   304 -----------------ESLTIGWPFLGPRQCVASEMTSLPMIVSVKEGGRTRPQVVSLPNMRVQ 351

  Fly   582 SCGC 585
            :|.|
Mouse   352 TCSC 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
daw	NP_001259967.1	TGFb_propeptide	244..458	CDD:279078	43/253 (17%)
		TGF_beta	481..585	CDD:278448	34/113 (30%)
Lefty2	NP_796073.1	TGFb_propeptide	<106..211	CDD:279078	26/115 (23%)
		TGF_beta	263..355	CDD:278448	34/113 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11848
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000